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There was also a significant excess of patients with the deficiency attending the renal unit, both among patients who had had renal transplants and those who had not. A familial incidence of monocyte esterase deficiency was found in 19 (35%) of first degree relatives of those patients in whom family studies were done. It is suggested that the reason for the increased prevalence of the anomaly in these disorders might be that the diminution of esterase activity has a role in their development.<\/jats:p>","DOI":"10.1136\/jcp.43.4.282","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"282-286","source":"Crossref","is-referenced-by-count":16,"title":["Monocyte esterase deficiency in malignant neoplasia."],"prefix":"10.1136","volume":"43","author":[{"given":"G M","family":"Markey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A","family":"McCormick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T C","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H D","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Nolan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L M","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M E","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Edgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A L","family":"Bell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M D","family":"McCaigue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1990,4,1]]},"reference":[{"key":"ref_1","first-page":"175","article-title":"Does a relationship exist between neutrophil myeloperoxidase deficiency and the occurrence of neoplasms","volume":"22","author":"Lanza, F.; Fietta, A.; Spisani, S.; Castoldi, G.L.; Traniello, S.","year":"1987","unstructured":"Lanza F, Fietta A, Spisani S, Castoldi GL, Traniello S. 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Am J Pathol 1971;55: 283-90.","journal-title":"Am J Pathol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1365-2141.1985.tb02886.x","article-title":"The relevance ofa naphthyl acetate esterase to various monocyte functions","volume":"61","author":"Oertel, J.; Hagner, G.; Kastner, M.; Huhn, D.","year":"1985","unstructured":"Oertel J, Hagner G, Kastner M, Huhn D. The relevance ofa naphthyl acetate esterase to various monocyte functions. 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