{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T09:39:56Z","timestamp":1765705196092,"version":"3.48.0"},"reference-count":12,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:p>Each year from 1981 through to 1988 the most common serotypes isolated from man in England and Wales and identified at the Division of Enteric Pathogens were S typhimurium, S enteritidis, and S virchow. In 1981 these three serotypes accounted for 45%, 12%, and 7% of isolations. The remaining 35% comprised strains belonging to a further 188 different serotypes, none of which accounted for more than 1% of the total. In 1988 S typhimurium accounted for 24% of isolations, S enteritidis 57%, and S virchow 4%. The remaining 15% comprised strains of a further 184 serotypes. The resistances to the common antimicrobial drugs in non-typhoidal salmonellas isolated in England and Wales in 1981 and 1988 were reported with particular reference to resistance to four or more antimicrobial drugs (multiple resistance). For S typhimurium the overall percentage of resistant strains varied little, but multiple resistance more than doubled from 5% to 12%; in S enteritidis the incidence remained the same. In S virchow the percentages of strains resistant to all the antimicrobial drugs and in particular, to chloramphenicol, streptomycin, trimethoprim and furazolidone, rose from 0.2% to 10.4%. Salmonella enteritis in man is usually a self limiting disease and antimicrobial treatment is seldom required; but should spread beyond the intestine occur, effective antimicrobial treatment is essential. Under these circumstances a knowledge of the likelihood of resistances to commonly available drugs could be of considerable value to the clinician.<\/jats:p>","DOI":"10.1136\/jcp.43.7.563","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"563-566","source":"Crossref","is-referenced-by-count":38,"title":["Multiple drug resistance in salmonellae in England and Wales: a comparison between 1981 and 1988."],"prefix":"10.1136","volume":"43","author":[{"given":"L R","family":"Ward","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E J","family":"Threlfall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Rowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1990,7,1]]},"reference":[{"key":"ref_1","article-title":"In: Serological diagnosis of salmonella species","author":"Kauffman, F.","year":"1972","unstructured":"Kauffman F. In: Serological diagnosis of salmonella species. Copenhagen: Munksgaard, 1972."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1017\/S0022172400020209","article-title":"A new phage-typing scheme for Salmonella typhimurium","volume":"57","author":"Callow, B.","year":"1959","unstructured":"Callow B. A new phage-typing scheme for Salmonella typhimurium. J Hyg 1959;57:346-59.","journal-title":"J Hyg"},{"key":"ref_3","first-page":"291","article-title":"A phage-typing scheme for Salmonella enteritidis Epidemiol Infect","volume":"99","author":"Ward, L.R.; de Sa, J.D.H.; Rowe, B.","year":"1978","unstructured":"Ward LR, de Sa JDH, Rowe B. A phage-typing scheme for Salmonella enteritidis Epidemiol Infect 1978;99:291-4."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1574-6968.1987.tb02016.x","article-title":"A phage-typing scheme for Salmonella virchow","volume":"40","author":"Chambers, R.M.; McAdam, P.; de Sa, J.D.H.; Ward, L.R.; Rowe, B.","year":"1987","unstructured":"Chambers RM, McAdam P, de Sa JDH, Ward LR, Rowe B. A phage-typing scheme for Salmonella virchow. FEMS Microbiol Lett 1987;40:155-7.","journal-title":"FEMS Microbiol Lett"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1017\/S0022172400023718","article-title":"Thecharacterizationofplasmids in the enterobacteria","volume":"72","author":"Anderson, E.S.; Threlfall, E.J.","year":"1974","unstructured":"Anderson ES, Threlfall EJ. Thecharacterizationofplasmids in the enterobacteria. J Hyg 1974;72:471-87.","journal-title":"J Hyg"},{"key":"ref_6","first-page":"265","article-title":"Methods of studying transferable resistance to antibiotics in vitro","volume-title":"Assessment of antimicrobial activity and resistance. SAB Technical Series","author":"Frost, J.A.; Threlfall, E.J.; Willshaw, G.A.","year":"1983","unstructured":"Frost JA, Threlfall EJ, Willshaw GA. Methods of studying transferable resistance to antibiotics in vitro. In: Russell AP, Quesnel LB, eds. Assessment of antimicrobial activity and resistance. SAB Technical Series: New York: Academic Press, 1983:265-84."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1017\/S095026880006711X","article-title":"Extraintestinal salmonellosis","volume":"100","author":"Wilkins, E.G.L.; Roberts, C.","year":"1988","unstructured":"Wilkins EGL, Roberts C. Extraintestinal salmonellosis. Epidemiol Infect 1988;100:361-8.","journal-title":"Epidemiol Infect"},{"key":"ref_8","first-page":"1242","article-title":"Bacteraemia in salmonellosis: a 15 year retrospective study from a regional infectious diseases unit","volume":"1988","author":"Mandal, B.K.; Brennand, J.","unstructured":"Mandal BK, Brennand J. Bacteraemia in salmonellosis: a 15 year retrospective study from a regional infectious diseases unit. Br Med J 1988:1242-3.","journal-title":"Br Med J"},{"key":"ref_9","first-page":"6","article-title":"Antibiotic resistance in salmonella","volume":"3","author":"Rowe, B.; Threlfall, E.J.","year":"1986","unstructured":"Rowe B, Threlfall EJ. Antibiotic resistance in salmonella. PHLS Microbiol Digest 1986;3:6-8.","journal-title":"PHLS Microbiol Digest"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1017\/S0022172400070066","article-title":"Characterization of resistance plasmids and carried phages in an epidemic clone ofmulti-resistant Salmonella typhimurium in India","volume":"88","author":"Frost, J.A.; Rowe, B.; Ward, L.R.; Threlfall, E.J.","year":"1982","unstructured":"Frost JA, Rowe B, Ward LR, Threlfall EJ. Characterization of resistance plasmids and carried phages in an epidemic clone ofmulti-resistant Salmonella typhimurium in India. J Hyg 1982;88:193-204.","journal-title":"J Hyg"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1136\/vr.120.15.366","article-title":"Increase in prevalence of a neomycin\/kanamycin-sensitive variant of S typhimurium PT204c in cattle in Britain","volume":"15","author":"Threlfall, E.J.; Rowe, B.; Ward, L.R.","year":"1987","unstructured":"Threlfall EJ, Rowe B, Ward LR. Increase in prevalence of a neomycin\/kanamycin-sensitive variant of S typhimurium PT204c in cattle in Britain. Vet Rec 1987;15:366-7.","journal-title":"Vet Rec"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1017\/S0950268800030594","article-title":"Acquisition of a drug resistance plasmid converts Salmonella enteritidis phage type 4 to phage type 24","volume":"103","author":"Frost, J.A.; Ward, L.R.; Rowe, B.","year":"1989","unstructured":"Frost JA, Ward LR, Rowe B. Acquisition of a drug resistance plasmid converts Salmonella enteritidis phage type 4 to phage type 24. Epidemiol Infect 1989;103:243-8.","journal-title":"Epidemiol Infect"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.43.7.563","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T09:35:53Z","timestamp":1765704953000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.43.7.563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":12,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1990,7,1]]},"published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1136\/jcp.43.7.563"],"URL":"https:\/\/doi.org\/10.1136\/jcp.43.7.563","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}