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In the stomach fundic gland polyps were the commonest abnormality, seen microscopically in 44 patients. Chronic antral gastritis was common in patients without fundic polyps. Gastric adenomas were present in six patients, all of whom also had duodenal adenomas. If duodenal adenomas in familial adenomatous polyposis have a similar malignant potential to those in the colorectum sequential endoscopy and biopsy are necessary to detect cancer in these patients.<\/jats:p>","DOI":"10.1136\/jcp.43.9.738","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"738-743","source":"Crossref","is-referenced-by-count":130,"title":["Upper gastrointestinal pathology in familial adenomatous polyposis: results from a prospective study of 102 patients."],"prefix":"10.1136","volume":"43","author":[{"given":"P","family":"Domizio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I C","family":"Talbot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A D","family":"Spigelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C B","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R K","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1990,9,1]]},"reference":[{"key":"ref_1","first-page":"614","volume":"328","author":"Nature","year":"1987","unstructured":"Nature 1987;328:614-6."},{"key":"ref_2","first-page":"429","article-title":"Uber Polyposis intestinalis adenomatosa und deren Beziehungen zur Krebsentwicklung. 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Semin Surg Oncol","volume":"3","author":"Lipkin, M.","year":"1987","unstructured":"Lipkin M. Colonic cell proliferation in familial polyposis. Semin Surg Oncol 1987;3:165-70."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0016-5085(19)33309-8","article-title":"Cell renewal in familial polyposis. Comparison between polyps and adjacent healthy mucosa","volume":"63","author":"Bleiberg, H.; Mainguet, P.; Galand, P.","year":"1972","unstructured":"Bleiberg H, Mainguet P, Galand P. Cell renewal in familial polyposis. Comparison between polyps and adjacent healthy mucosa. Gastroenterol 1972;63:240-5.","journal-title":"Gastroenterol"},{"key":"ref_36","first-page":"175","article-title":"Study of human rectal epithelial cells in vitro. III. RNA, protein, and DNA synthesis in polyps and adjacent mucosa","volume":"44","author":"Deschner, E.E.; Lipkin, M.","year":"1970","unstructured":"Deschner EE, Lipkin M. Study of human rectal epithelial cells in vitro. III. RNA, protein, and DNA synthesis in polyps and adjacent mucosa. JNCI 1970;44:175-85.","journal-title":"JNCI"},{"key":"ref_37","first-page":"43","article-title":"Phase 1 and phase 2 proliferative lesions ofcolonic epithelial cells in diseases leading to colon cancer","volume":"1974","author":"Lipkin, M.","unstructured":"Lipkin M. Phase 1 and phase 2 proliferative lesions ofcolonic epithelial cells in diseases leading to colon cancer. Cancer 1974;(suppl) 43:878-88.","journal-title":"Cancer"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1002\/1097-0142(19810515)47:10<2440::AID-CNCR2820471022>3.0.CO;2-F","article-title":"Kinetic and morphologic alterations in the colon of a patient with multiple polyposis","volume":"47","author":"Deschner, E.E.; Raicht, R.F.","year":"1981","unstructured":"Deschner EE, Raicht RF. Kinetic and morphologic alterations in the colon of a patient with multiple polyposis. 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