{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:15:45Z","timestamp":1792304145838,"version":"4.4.0"},"reference-count":9,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:p>A total of 31 cervical biopsy specimens were taken from 29 women attending a genitourinary medicine clinic, nine women (11 biopsy specimens) were known to have Chlamydia trachomatis cervicitis and 20 women were known to be free of chlamydial infection. The specimens were routinely processed to paraffin wax and stained by an anti-Chlamydia immunoperoxidase technique to localise the organisms. Of the 11 positive biopsy specimens three showed positive staining of elementary\/reticulate bodies. In one case the surface endocervical cells showed large inclusions which were packed with chlamydial bodies. The diagnosis of chlamydial infection is difficult to make clinically and in routine cytological and histological specimens but immunoperoxidase staining can clearly identify C trachomatis inclusions in cervical biopsy specimens provided infection is severe.<\/jats:p>","DOI":"10.1136\/jcp.44.12.1027","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"1027-1029","source":"Crossref","is-referenced-by-count":7,"title":["Demonstration of Chlamydia trachomatis in colposcopic cervical biopsy specimens by an immunoperoxidase method."],"prefix":"10.1136","volume":"44","author":[{"given":"J M","family":"Edwards","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A R","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Tait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Lusher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1991,12,1]]},"reference":[{"key":"ref_1","article-title":"Health and Human Services. Chlamydia trachomatis infections. Policy guidelines for prevention and control. US Department of Health and Human Services","author":"US Department of","year":"1985","unstructured":"US Department of Health and Human Services. Chlamydia trachomatis infections. Policy guidelines for prevention and control. US Department of Health and Human Services. Atlanta, Georgia: Centers for Disease Control, 1985."},{"key":"ref_2","first-page":"309","article-title":"Evaluation of proposed cytomorphologic criteria for the diagnosis of Chlamydia trachomatis in Papanicolaou smears","volume":"33","author":"Bernal, J.N.; Martineq, M.A.; Dabancens, A.","year":"1988","unstructured":"Bernal JN, Martineq MA, Dabancens A. Evaluation of proposed cytomorphologic criteria for the diagnosis of Chlamydia trachomatis in Papanicolaou smears. 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Colposcopy, biopsy, and cytology results in women with chlamydial cervicitis. Genitourin Med 1989;65:22-31.","journal-title":"Genitourin Med"},{"key":"ref_5","first-page":"997","article-title":"Cytological manifestations of cervical and vaginal infections","volume":"253","author":"Kiviat, N.B.; Peterson, M.; Kinney-Thomas, E.; Tam, M.; Stamm, W.E.; Holmes, K.K.","year":"1985","unstructured":"Kiviat NB, Peterson M, Kinney-Thomas E, Tam M, Stamm WE, Holmes KK. Cytological manifestations of cervical and vaginal infections. JAMA 1985;253:997-1000.","journal-title":"JAMA"},{"issue":"11","key":"ref_6","first-page":"1","article-title":"Immunoperoxidase demonstration of chlamydia inclusions in routine Pap smears","volume":"1982","author":"Leopardi 0, Celentano C, Naughten W","unstructured":"Leopardi 0, Celentano C, Naughten W. Immunoperoxidase demonstration of chlamydia inclusions in routine Pap smears. Eur J Gynaecol Oncol 1982;-11:1-19-22.","journal-title":"Eur J Gynaecol Oncol"},{"key":"ref_7","first-page":"1246","article-title":"Non-invasive sampling method for detecting Chlamydia trachomatis","volume":"ii:","author":"Caul, E.O.; Paul, I.D.; Milner, J.D.; Crowley, T.","year":"1988","unstructured":"Caul EO, Paul ID, Milner JD, Crowley T. Non-invasive sampling method for detecting Chlamydia trachomatis. Lancet 1988;ii:1246-7.","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1699-0463.1989.tb00757.x","article-title":"Detection of chlamydia in posatmortal formalin fixed tissue","volume":"97","author":"Lundermose, A.G.; Lundemose, J.B.; Birkelund, S.; Christiansen, G.","year":"1989","unstructured":"Lundermose AG, Lundemose JB, Birkelund S, Christiansen G. Detection of chlamydia in posatmortal formalin fixed tissue. 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