{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T11:49:41Z","timestamp":1758800981299,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1992,12]]},"abstract":"<jats:p>A previously unreported cell phenotype occurred in the pyloric and Brunner glands in two gastrectomy specimens. The cells were characterised by homogeneous, eosinophilic material in the cytoplasm. The eosinophilic material had an abnormally strong reactivity for Cystatin C, a protein found recently in the normal secretion of pyloric and Brunner's gland cells. The reason for the apparent cytoplasmic accumulation of cystatin C in the two patients described remains unclear.<\/jats:p>","DOI":"10.1136\/jcp.45.12.1119","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"1119-1120","source":"Crossref","is-referenced-by-count":1,"title":["Eosinophilic bodies in pyloric and Brunner's gland cells."],"prefix":"10.1136","volume":"45","author":[{"given":"C A","family":"Rubio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Hirota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Itabashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Jacobsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Lignelid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1992,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0074-7696(08)61133-X","article-title":"The cells of the gastric mucosa","volume":"70","author":"Helander, H.F.","year":"1981","unstructured":"Helander HF. The cells of the gastric mucosa. Int Rev Cytol 1981;70:217-89 2 Junqueira LC, Carneiro J. Digestive tract. In: Basic histology","journal-title":"Int Rev Cytol; Digestive tract"},{"key":"ref_2","article-title":"Normal histology of the stomach","author":"Owen, D.A.","year":"1986","unstructured":"Owen DA. Normal histology of the stomach. Am J Surg Pathol 1986;10:48-61 4 Rhodin JAG. The alimentary system. In: Histology: A text and atlas. London: Oxford University Press","journal-title":"Am J Surg Pathol; 10: 48-61 4 Rhodin JAG. The alimentary system. In: Histology: A text and atlas"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0344-0338(11)81173-8","article-title":"Five types of pyloric cells in the antral mucosa of the stomach","volume":"188","author":"Rubio, C.A.","year":"1992","unstructured":"Rubio CA. Five types of pyloric cells in the antral mucosa of the stomach. Path Res Pract 1992;188:157-61.","journal-title":"Path Res Pract"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1042\/bj2680287","article-title":"Structure and expression of the human cystatin C gene","volume":"268","author":"Abrahamson, M.; Olafsson, I.; Palsdottir, A.","year":"1990","unstructured":"Abrahamson M, Olafsson I, Palsdottir A, et al. Structure and expression of the human cystatin C gene. Biochem J 1990;268:287-94.","journal-title":"Biochem J"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0344-0338(88)80129-8","article-title":"Six types of intraepithelial vacuoles in the human gastric mucosa","volume":"183","author":"Rubio, C.A.; KatoY","year":"1988","unstructured":"Rubio CA, KatoY. Six types of intraepithelial vacuoles in the human gastric mucosa. Path Res Pract 1988;183: 321-25.","journal-title":"Path Res Pract"},{"key":"ref_6","first-page":"165","article-title":"A pitfall in the interpretation of intestinal metaplasia of the stomach","volume":"94","author":"Rubio, C.A.; Kato, Y.; Kitagawa, T.; Sugano, H.","year":"1986","unstructured":"Rubio CA, Kato Y, Kitagawa T, Sugano H. A pitfall in the interpretation of intestinal metaplasia of the stomach. Acta Pathol Microbiol Immunol Scand (A) 1986; 94:165-6.","journal-title":"Acta Pathol Microbiol Immunol Scand (A)"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"\"1067","DOI":"10.1111\/j.1365-2559.1987.tb01846.x","article-title":"Subnuclear vacuolated mucous cells: a novel abnormality of simple mucinsecreting cells of non-specialised gastric mucosa and Brunner's glands","volume":"11","author":"Thompson, I.W.; Day, D.W.; Wright, N.A.","year":"1987","unstructured":"Thompson IW, Day DW, Wright NA. Subnuclear vacuolated mucous cells: a novel abnormality of simple mucinsecreting cells of non-specialised gastric mucosa and Brunner's glands. Histopathology 1987;11:1067-81. Jr Clin Pathol 1992;45:1120-1121","journal-title":"Histopathology"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.45.12.1119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T11:15:59Z","timestamp":1758798959000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.45.12.1119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12]]},"references-count":7,"journal-issue":{"issue":"12","published-online":{"date-parts":[[1992,12,1]]},"published-print":{"date-parts":[[1992,12]]}},"alternative-id":["10.1136\/jcp.45.12.1119"],"URL":"https:\/\/doi.org\/10.1136\/jcp.45.12.1119","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1992,12]]}}}