{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:15:29Z","timestamp":1758845729498,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:p>The clinical, histological, and necropsy findings of three cases of fatal, nonmalignant ulceration in the gastric tube after oesophageal resection for oesophageal malignancy are presented. The deaths occurred three, 30, and 42 months, respectively, after initial surgery. Two of the patients had received chemoradiotherapy, one at initial presentation, and one for a recurrence 18 months after surgery. In two patients death was due to an aspiration pneumonia, consequent on the development of a gastrobronchial fistula. The third patient died after a massive haematemesis. In none of the cases was there any evidence of residual or recurrent malignancy at necropsy, although in the two cases where radiological and endoscopic assessment was performed before death, recurrent tumour had been clinically diagnosed. As improved surgical techniques reduce the incidence of death due to anastomotic leakage and combined modality treatment regimens offer improved prospects of tumour remission, deaths from other causes will assume a greater importance. As such, the possibility that ulceration in the gastric tube may be due to causes other than tumour recurrence deserves greater recognition.<\/jats:p>","DOI":"10.1136\/jcp.46.5.483","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"483-485","source":"Crossref","is-referenced-by-count":21,"title":["Fatal non-malignant ulceration in the gastric tube after oesophagectomy."],"prefix":"10.1136","volume":"46","author":[{"given":"M","family":"McDermott","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D O","family":"Hourihane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1993,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/S0140-6736(65)91214-6","article-title":"Pathogenesis of gastric ulceration","volume":"i:","author":"DJ, Du Plessis","year":"1965","unstructured":"Du Plessis DJ. 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J Thorac Cardiovasc Surg 1983;85:827-31.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref_6","first-page":"611","article-title":"Surgery of the oesophagus","author":"In, Wong J.","year":"1988","unstructured":"Wong J. In: Jamieson GG ed. Surgery of the oesophagus. Edinburgh: Churchill Livingstone, 1988:611-18."},{"key":"ref_7","first-page":"476","article-title":"Role of ischaemia in the initiation of peptic ulceration Ann Roy Coil Surg Engi","volume":"59","author":"Piasecli, C.","year":"1977","unstructured":"Piasecli C. Role of ischaemia in the initiation of peptic ulceration Ann Roy Coil Surg Engi 1977;59:476-8."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF01658286","article-title":"Role of bile acid reflux in acute haemorrhagic gastritis","volume":"5","author":"Ritchie, W.","year":"1981","unstructured":"Ritchie W. Role of bile acid reflux in acute haemorrhagic gastritis. WorldJ Surg 1981;5:189-94.","journal-title":"WorldJ Surg"},{"key":"ref_9","first-page":"362","article-title":"In: Radiation oncology, rationale, techniques, results","author":"Moss, W.T.","year":"1979","unstructured":"Moss WT. In: Radiation oncology, rationale, techniques, results. 5th edn. London: CV Mosby, 1979:362-5.","edition":"5th edn"},{"key":"ref_10","first-page":"1201","article-title":"Mucosal injury and gamma-irradiation produce persistent gastric ulcers","volume-title":"the rabbit. Gastroenterology 1991","volume":"100","author":"Yokel, R.","unstructured":"Yokel R Mucosal injury and gamma-irradiation produce persistent gastric ulcers in the rabbit. Gastroenterology 1991;100: 1201-5."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.46.5.483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:39:10Z","timestamp":1758796750000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.46.5.483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,5]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1993,5,1]]},"published-print":{"date-parts":[[1993,5]]}},"alternative-id":["10.1136\/jcp.46.5.483"],"URL":"https:\/\/doi.org\/10.1136\/jcp.46.5.483","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1993,5]]}}}