{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:33:22Z","timestamp":1765596802013,"version":"3.48.0"},"reference-count":7,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1994,3]]},"abstract":"<jats:p>Multiple myeloma is a neoplastic disorder caused by the proliferation of a transformed B lymphoid progenitor cell that gives rise to a clone of immunoglobulin-secreting cells. Other plasma cell tumours include solitary plasmacytoma of bone (SPB) and extramedullary plasmacytomas (EMP). Despite an apparent common origin there exist pathological and clinical differences between these neoplasms and the association between them is not completely understood. A case of IgG multiple myeloma that presented with typical clinical and laboratory features, including a bone marrow infiltrated by well differentiated plasma cells, is reported. The tumour had an unusual evolution, with the development of extensive extramedullary disease while maintaining mature histological features.<\/jats:p>","DOI":"10.1136\/jcp.47.3.269","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"269-271","source":"Crossref","is-referenced-by-count":8,"title":["Atypical progression of multiple myeloma with extensive extramedullary disease."],"prefix":"10.1136","volume":"47","author":[{"given":"S N","family":"Jowitt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Batman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Sapherson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1001\/archinte.1975.00330010089012","article-title":"Pruzanski W: IgD myeloma. 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Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumours of bone. J Clin Oncol 1983; 1:255-62.","journal-title":"J Clin Oncol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/00005792-197605000-00002","article-title":"The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis","volume":"55","author":"Wiltshaw, E.","year":"1976","unstructured":"Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine 1976;55:217-38.","journal-title":"Medicine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/1097-0142(197903)43:3<1007::AID-CNCR2820430333>3.0.CO;2-4","article-title":"Solitary plasmacytoma of bone vs. extramedullary plasmacytoma and their relationship to multiple myeloma","volume":"43","author":"Corwin, J.; Lindberg, R.D.","year":"1979","unstructured":"Corwin J, Lindberg RD. Solitary plasmacytoma of bone vs. extramedullary plasmacytoma and their relationship to multiple myeloma. Cancer 1979;43:1007-13.","journal-title":"Cancer"},{"key":"ref_7","first-page":"23","article-title":"Mandard AM: Plasmacytoma with asynchronous metastasis. Immunological and ultrastructural contribution","volume":"40","author":"Bauduer, F.; Tanguy, A.","year":"1992","unstructured":"Bauduer F, Tanguy A, Mandard AM: Plasmacytoma with asynchronous metastasis. Immunological and ultrastructural contribution. Arch Anat Cytol Pathol 1992;40:23-7.","journal-title":"Arch Anat Cytol Pathol"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.47.3.269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:31:07Z","timestamp":1765596667000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.47.3.269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1994,3,1]]},"published-print":{"date-parts":[[1994,3]]}},"alternative-id":["10.1136\/jcp.47.3.269"],"URL":"https:\/\/doi.org\/10.1136\/jcp.47.3.269","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1994,3]]}}}