{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:21:31Z","timestamp":1760188891421,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:p>A 76 year old man was admitted for evaluation and treatment of acute oligoarticular arthritis having recently returned from India. He was diabetic on admission. Neisseria gonorrhoeae was isolated from pus collected by arthrocentesis of his right knee and was subsequently found to be chromosomally resistant to penicillin. The isolate required proline for growth and expressed the protein 1B-1 serovar. These characteristics of host and pathogen are atypical in that gonococcal arthritis usually occurs in young women and is usually caused by N gonorrhoeae isolates exhibiting hypersusceptibility to penicillin, the arginine, hypoxanthine and uracil requiring auxotype, and the protein 1A serotype. The patient responded well to therapy with oral ciprofloxacin and initial high dose penicillin.<\/jats:p>","DOI":"10.1136\/jcp.48.1.86","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"86-88","source":"Crossref","is-referenced-by-count":3,"title":["Acute gonococcal arthritis: an unusual host and pathogen combination."],"prefix":"10.1136","volume":"48","author":[{"given":"D A","family":"Lewis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L M","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Randell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P G","family":"Kopelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1995,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/bmj.1.5747.482","article-title":"Septic gonococcal dermatitis","volume":"1","author":"Barr, J.; Danielsson, D.","year":"1971","unstructured":"Barr J, Danielsson D. 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JInfect Dis 1975;132:204-8.","journal-title":"JInfect Dis"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/infdis\/154.2.225","article-title":"Auxotypes, penicillin susceptibility and serogroups of Neisseria gonorrhoeae from disseminated and uncomplicated infections","volume":"154","author":"Bohnhoff, M.; Morello, J.A.; Lerner, S.A.","year":"1986","unstructured":"Bohnhoff M, Morello JA, Lerner SA. Auxotypes, penicillin susceptibility and serogroups of Neisseria gonorrhoeae from disseminated and uncomplicated infections. J Infect Dis 1986;154:225-30.","journal-title":"J Infect Dis"},{"key":"ref_8","first-page":"283","article-title":"Septic gonococcal arthritis is much more common in the","volume":"29","author":"Hook, E.W.","year":"1990","unstructured":"Hook EW. Septic gonococcal arthritis is much more common in the USA than in the UK. Br J Rheumatol 1990;29:283.","journal-title":"USA than in the UK. Br J Rheumatol"},{"key":"ref_9","first-page":"340","article-title":"Chromosomally mediated resistance in Neisseria gonorrhoeae in the United States: results of surveillance and reporting, 1983-1984. J7 Infect Dis","volume":"153","author":"Rice, R.J.; Biddle, J.W.; JeanLouis, Y.A.; Dewitt, W.E.; Blount, J.H.; Morse, S.A.","year":"1986","unstructured":"Rice RJ, Biddle JW, JeanLouis YA, Dewitt WE, Blount JH, Morse SA. Chromosomally mediated resistance in Neisseria gonorrhoeae in the United States: results of surveillance and reporting, 1983-1984. 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