{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:23:27Z","timestamp":1764995007188,"version":"3.46.0"},"reference-count":10,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1996,2]]},"abstract":"<jats:p>The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barrett's mucosa (15%) and in 26 gastric mucosa specimens (35.6%). All cases positive in Barrett's mucosa were also positive in the stomach. In Barrett's oesophagus, H pylori was never found on specialised epithelium. The percentage of Barrett's mucosa showing inflammatory changes was similar in specimens with and without H pylori, both for chronic (81% v 79%) and acute (9% v 10%) infiltrates. These results indicate that H pylori infection does not play an aetiological role in Barrett's oesophagus and that colonisation of the metaplastic mucosa by this bacteria is related with the presence of gastric type mucosa in the oesophagus and of H pylori infection in the stomach.<\/jats:p>","DOI":"10.1136\/jcp.49.2.176","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"176-177","source":"Crossref","is-referenced-by-count":19,"title":["Helicobacter pylori infection in patients with Barrett's oesophagus: a prospective immunohistochemical study."],"prefix":"10.1136","volume":"49","author":[{"given":"O","family":"Ricaurte","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"Fl\u00e9jou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Vissuzaine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Goldfain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Rotenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Cadiot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Potet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1996,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJM197608262950904","article-title":"The histologic spectrum of Barrett esophagus","volume":"295","author":"Paull, A.; Trier, J.S.; Dalton, M.D.; Camp, R.C.; Loeb, P.; Goyal, R.K.","year":"1976","unstructured":"Paull A, Trier JS, Dalton MD, Camp RC, Loeb P, Goyal RK. The histologic spectrum of Barrett esophagus. N Engl J Med 1976;295:476-80.","journal-title":"N Engl J Med"},{"key":"ref_2","first-page":"1176","article-title":"Campylobacter pylori and Barrett's oesophagus","volume-title":"Mayo Clin Proc 1988; 63","author":"Talley, N.J.; Cameron, A.J.; Shorter, R.G.; Zinsmeister, A.R.; Phillips, S.F.","unstructured":"Talley NJ, Cameron AJ, Shorter RG, Zinsmeister AR, Phillips SF. Campylobacter pylori and Barrett's oesophagus. Mayo Clin Proc 1988;63:1176-80."},{"issue":"2","key":"ref_3","first-page":"16","article-title":"Gastric and esophageal Campylobacter pylori in patients with Barrett's esophagus","volume":"95","author":"Paull, G.; Yardley, J.H.","year":"1988","unstructured":"Paull G, Yardley JH. Gastric and esophageal Campylobacter pylori in patients with Barrett's esophagus. Gastroenterology 1988;95:2 16-8.","journal-title":"Gastroenterology"},{"key":"ref_4","first-page":"470","article-title":"Absence of Campylobacter-like organisms in Barrett's esophagus","volume":"113","author":"Houck, J.A.; Lucas, J.G.","year":"1989","unstructured":"Houck JA, Lucas JG. Absence of Campylobacter-like organisms in Barrett's esophagus. Arch Pathol Lab Med 1989; 113:470-2.","journal-title":"Arch Pathol Lab Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1007\/BF01540063","article-title":"Campylobacter pylori in esophagus","volume":"34","author":"Fallingborg, J.; Agnholt, J.; Moller-Petersen, J.; Christensen, L.A.; Lomborg, S.; Sondergaard, G.","year":"1989","unstructured":"Fallingborg J, Agnholt J, Moller-Petersen J, Christensen LA, Lomborg S, Sondergaard G, et al. Campylobacter pylori in esophagus. Dig Dis Sci 1989;34:1802-3.","journal-title":"Dig Dis Sci"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1136\/gut.30.10.1334","article-title":"Patterns ofcolonisation of Campylobacter pylori in the oesophagus, stomach and duodenum","volume":"30","author":"Walker, S.J.; Birch, P.J.; Stewart, M.; Stoddard, C.J.; Hart, C.A.; Day, D.W.","year":"1989","unstructured":"Walker SJ, Birch PJ, Stewart M, Stoddard CJ, Hart CA, Day DW. Patterns ofcolonisation of Campylobacter pylori in the oesophagus, stomach and duodenum. Gut 1989; 30:1334-8.","journal-title":"Gut"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1093\/infdis\/162.6.1414","article-title":"Helicobacter pylori: has it a part in the lesion of the gastroesophageal reflux?","volume":"162","author":"Francoual, S.; Ph, Lamy; Le Quintrec, Y.; Luboinski, J.; Petit, J.C.","year":"1990","unstructured":"Francoual S, Lamy Ph, Le Quintrec Y, Luboinski J, Petit JC. Helicobacter pylori: has it a part in the lesion of the gastroesophageal reflux? J Infect Dis 1990;162:1414.","journal-title":"J Infect Dis"},{"key":"ref_8","first-page":"568","article-title":"Gruppo Operativo Per Lo Studio Delle Precancerosi Esofagee (GOSPE). Helicobacter pylori in Barrett's oesophagus","volume":"18","year":"1991","unstructured":"Gruppo Operativo Per Lo Studio Delle Precancerosi Esofagee (GOSPE). Helicobacter pylori in Barrett's oesophagus. Histopathology 1991;18:568-70.","journal-title":"Histopathology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-1746.1991.tb01137.x","article-title":"Barrett's oesophagus","volume":"6","author":"Dent, J.; Bremner, C.G.; Collen, M.J.; Haggitt, R.C.; Spechler, S.J.","year":"1991","unstructured":"Dent J, Bremner CG, Collen MJ, Haggitt RC, Spechler SJ. Barrett's oesophagus. J Gastroenterol Hepatol 1991;6:1-22.","journal-title":"J Gastroenterol Hepatol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"\"559","DOI":"10.1111\/j.1699-0463.1988.tb05344.x","article-title":"Campylobacter pylori detected by indirect immunohistochemical technique","volume":"96","author":"Andersen, L.P.; Holck, S.; Poulsen, C.O.","year":"1988","unstructured":"Andersen LP, Holck S, Poulsen CO. Campylobacter pylori detected by indirect immunohistochemical technique. APMIS 1988;96:559-64. 7 Clin Pathol 1996;49:177-179","journal-title":"APMIS"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.49.2.176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T03:25:26Z","timestamp":1764991526000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.49.2.176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1996,2,1]]},"published-print":{"date-parts":[[1996,2]]}},"alternative-id":["10.1136\/jcp.49.2.176"],"URL":"https:\/\/doi.org\/10.1136\/jcp.49.2.176","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1996,2]]}}}