{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:16:14Z","timestamp":1791904574914,"version":"4.3.4"},"reference-count":7,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:p>AIMS: To investigate the serological cross reaction between legionella and campylobacter using the rapid microagglutination test (RMAT). METHODS: Serum samples from 49 patients with campylobacter infection were tested for legionella antibodies using the indirect fluorescent antibody test (IFAT) and the RMAT. Serum samples that had positive RMAT titres were retested in the presence of a campylobacter immunosorbent. The specificity of the immunosorbent was evaluated with serum from patients with genuine legionella infection (legionella culture or antigen positive, or both). RESULTS: Fourteen (28%) patients with campylobacter infection had positive IFAT titres (&gt; or = 16) and 16 (32%) patients had positive RMAT titres (&gt; or = 8) in one or more serum samples. In addition, serum samples from 11 of 17 patients with campylobacter infection, previously shown to have positive legionella IFAT titres, were also RMAT positive. Sixteen patients had RMAT titres of &gt; or = 32, including seven with titres of &gt; or = 128. RMAT titres from all but one patient were significantly reduced after campylobacter absorption, but serum samples from 48 patients with legionella infection were unaffected. CONCLUSIONS: Serological cross reaction between campylobacter and legionella can occur in the legionella RMAT, as well as the IFAT. This cross reaction can be eliminated in most cases by incorporating a campylobacter immunosorbent in the RMAT.<\/jats:p>","DOI":"10.1136\/jcp.49.7.584","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"584-586","source":"Crossref","is-referenced-by-count":10,"title":["Serological cross reaction between legionella and campylobacter in the rapid microagglutination test."],"prefix":"10.1136","volume":"49","author":[{"given":"T C","family":"Boswell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1996,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1017\/S095026880005024X","article-title":"Serological cross-reaction between Legionella pneumophila and campylobacter in the indirect fluorescent antibody test","volume":"109","author":"Boswell, T.C.J.; Kudesia, G.","year":"1992","unstructured":"Boswell TCJ, Kudesia G. Serological cross-reaction between Legionella pneumophila and campylobacter in the indirect fluorescent antibody test. Epidemiol Infect 1992;109:291-5.","journal-title":"Epidemiol Infect"},{"key":"ref_2","first-page":"113","article-title":"The diagnosis of Legionnaires' disease by estimation of antibody levels","volume-title":"A laboratory manualfor legionella","author":"Harrison, T.G.; Taylor, A.G.","year":"1988","unstructured":"Harrison TG, Taylor AG. The diagnosis of Legionnaires' disease by estimation of antibody levels. In: Harrison TG, Taylor AG, eds. A laboratory manualfor legionella. Chichester: John Wiley and Sons Ltd, 1988:113-35."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1017\/S0950268800057757","article-title":"False positive Legionella serology in Campylobacter infection: Campylobacter serotypes, duration of antibody response and elimination of cross-reactions in the indirect fluorescent antibody test","volume":"112","author":"Marshall, L.E.; Boswell, T.C.J.; Kudesia, G.","year":"1994","unstructured":"Marshall LE, Boswell TCJ, Kudesia G. False positive Legionella serology in Campylobacter infection: Campylobacter serotypes, duration of antibody response and elimination of cross-reactions in the indirect fluorescent antibody test. Epidemiol Infect 1994;112:347-57.","journal-title":"Epidemiol Infect"},{"key":"ref_4","first-page":"23","article-title":"False-positive Legionella titres in routine clinical serology testing fdoertetchteedsberyolaobgsiocrapltidoinagwniotsihsCaomfpLyelgoiboancntaeirr:esi'mpdliisceaatsei.onJs Infect","volume":"32","author":"Boswell, T.C.; Marshall, L.E.; Kudesia, G.","year":"1996","unstructured":"Boswell TC, Marshall LE, Kudesia G. False-positive Legionella titres in routine clinical serology testing fdoertetchteedsberyolaobgsiocrapltidoinagwniotsihsCaomfpLyelgoiboancntaeirr:esi'mpdliisceaatsei.onJs Infect 1996;32:23-6."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0140-6736(92)91750-3","article-title":"Crossreactions between Legionella and Campylobacter spp","volume":"340","author":"Boswell, T.C.; Marshall, L.E.; Kudesia, G.","year":"1992","unstructured":"Boswell TC, Marshall LE, Kudesia G. Crossreactions between Legionella and Campylobacter spp. Lancet 1992; 340:551.","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"690","DOI":"10.7326\/0003-4819-90-4-690","article-title":"Immunoglobulin specificity of the microagglutination test for the Legionnaires'","volume":"90","author":"Farshy, C.E.; Cruce, D.D.; Klein, G.C.; Wilkinson, H.W.; Feeley, J.C.","year":"1979","unstructured":"Farshy CE, Cruce DD, Klein GC, Wilkinson HW, Feeley JC. Immunoglobulin specificity of the microagglutination test for the Legionnaires' disease bacterium. Ann Intern Med 1979;90:690.","journal-title":"disease bacterium. Ann Intern Med"},{"key":"ref_7","first-page":"77","article-title":"Evaluation of sneinasictaiuvsiteydobfytLweogisoenroellolgaicpanleutemsotsphfiorladisaegrnoogsrionugpp1n.eJuf mCloi-n Pathol","volume":"40","author":"Harrison, T.G.; Dournon, E.; Taylor, A.G.","year":"1987","unstructured":"Harrison TG, Dournon E, Taylor AG. Evaluation of sneinasictaiuvsiteydobfytLweogisoenroellolgaicpanleutemsotsphfiorladisaegrnoogsrionugpp1n.eJuf mCloi-n Pathol 1987;40:77-82."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.49.7.584","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:48:46Z","timestamp":1765597726000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.49.7.584"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":7,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1996,7,1]]},"published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1136\/jcp.49.7.584"],"URL":"https:\/\/doi.org\/10.1136\/jcp.49.7.584","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}