{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:16:20Z","timestamp":1770822980105,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:p>AIMS: To determine the cost and sensitivity of sputum cytology in routine use and to determine when sputum cytology is most appropriate. METHODS: A retrospective study, based on all sputum cytology requests received in five histopathology\/cytopathology laboratories in Yorkshire from 1 January to 31 December 1993. Cytology findings were correlated with histological diagnosis or clinical outcome, and related to the speciality of the referring clinician. RESULTS: Laboratory practice and performance was similar in all five centres. The average laboratory cost of sputum cytology was 26.93. The mean absolute sensitivity was 36% and the specificity was 99.6%. The majority of specimens was submitted by general physicians or geriatricians. The largest proportion of positive specimens were submitted by chest physicians. CONCLUSIONS: Often sputum cytology is used inappropriately as a screening investigation on, or soon after, admission. In addition, it is used inappropriately before bronchoscopy. Sputum cytology should be limited to individuals in whom a histological diagnosis is desired, but in whom bronchoscopy is inappropriate or unsuccessful.<\/jats:p>","DOI":"10.1136\/jcp.50.7.566","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"566-568","source":"Crossref","is-referenced-by-count":14,"title":["Sputum cytology: a limited role."],"prefix":"10.1136","volume":"50","author":[{"given":"A","family":"Gledhill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Bates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"DaCosta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1997,7,1]]},"reference":[{"key":"ref_1","article-title":"Critical path: an analysis of the pathology services","author":"Commission, Audit","year":"1993","unstructured":"Audit Commission. Critical path: an analysis of the pathology services. London: HMSO, 1993."},{"key":"ref_2","first-page":"99","article-title":"Cytological diagnosis of lung cancer","volume":"8","author":"Koss, I.G.","year":"1958","unstructured":"Koss IG. Cytological diagnosis of lung cancer. Acta Cytologica PatholJ7pn 1958;8:99-111.","journal-title":"Acta Cytologica PatholJ7pn"},{"key":"ref_3","first-page":"598","article-title":"Techniques in pulmonary cytopathology","volume":"46","author":"Young, J.A.","year":"1993","unstructured":"Young JA. Techniques in pulmonary cytopathology. J Clin Pathol 1993;46:598-5.","journal-title":"J Clin Pathol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/thx.42.3.165","article-title":"Predictive value of sputum cytology","volume":"42","author":"Benbassaat, J.; Regev, A.; Slater, P.E.","year":"1987","unstructured":"Benbassaat J, Regev A, Slater PE. Predictive value of sputum cytology. Thorax 1987;42:165-72.","journal-title":"Thorax"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/dc.2840070407","article-title":"Changing utilization of cytopathology versus histopathology in the diagnosis of lung cancer","volume":"7","author":"Fraire, A.F.; McLarty, J.W.; Greenberg, S.D.","year":"1991","unstructured":"Fraire AF, McLarty JW, Greenberg SD. Changing utilization of cytopathology versus histopathology in the diagnosis of lung cancer. Diagn Cytopathol 1991;7:359-62.","journal-title":"Diagn Cytopathol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1136\/bmj.310.6980.624","article-title":"Prospective study of combined use of bronchial aspirates and biopsy specimens in diagnosis and typing of centrally located lung tumours","volume":"310","author":"Piaton, E.; Grillet-Ravigneaux, M.; Suagier, B.; Pellet, H.","year":"1995","unstructured":"Piaton E, Grillet-Ravigneaux M, Suagier B, Pellet H. Prospective study of combined use of bronchial aspirates and biopsy specimens in diagnosis and typing of centrally located lung tumours. BMJ 1995;310:624-7.","journal-title":"BMJ"},{"key":"ref_7","first-page":"379","article-title":"Diagnosis and typing of lung cancers by cytopathological methods: a review of 108 cases","volume":"29","author":"Truong, L.D.; Underwood, R.U.; Greenberg, S.D.; McLarty, J.W.","year":"1985","unstructured":"Truong LD, Underwood RU, Greenberg SD, McLarty JW. Diagnosis and typing of lung cancers by cytopathological methods: a review of 108 cases. Acta Cytologica 1985;29: 379-84.","journal-title":"Acta Cytologica"},{"key":"ref_8","first-page":"49","article-title":"Cytological and histological correlation in primary lung cancer-a study of 154 cases with resectable tumours","volume":"29","author":"Tanaka, T.; Yamamoto, M.; Tamaru, T.; Moritani, Y.; Miyai, M.; Hiraki, S.","year":"1985","unstructured":"Tanaka T, Yamamoto M, Tamaru T, Moritani Y, Miyai M, Hiraki S, et al. Cytological and histological correlation in primary lung cancer-a study of 154 cases with resectable tumours. Acta Cytol 1985;29:49-56.","journal-title":"Acta Cytol"},{"key":"ref_9","first-page":"560","article-title":"Cytopathological diagnosis of cancer in pulmonary material: a critical histopathological correlation","volume":"14","author":"Erozan, Y.S.; Frost, J.K.","year":"1970","unstructured":"Erozan YS, Frost JK. Cytopathological diagnosis of cancer in pulmonary material: a critical histopathological correlation. Acta Cytol 1970;14:560-5.","journal-title":"Acta Cytol"},{"key":"ref_10","first-page":"103","article-title":"Ten years of respiratory cytopathology at Duke University Medical Center","volume":"25","author":"Johnston, W.W.; Bossen, E.H.","year":"1981","unstructured":"Johnston WW, Bossen EH. Ten years of respiratory cytopathology at Duke University Medical Center. Acta Cytol 1981;25:103-7.","journal-title":"Acta Cytol"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.50.7.566","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:44:37Z","timestamp":1758797077000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.50.7.566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1997,7,1]]},"published-print":{"date-parts":[[1997,7]]}},"alternative-id":["10.1136\/jcp.50.7.566"],"URL":"https:\/\/doi.org\/10.1136\/jcp.50.7.566","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}