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Sera from 14 H pylori infected patients with anticanalicular autoantibodies were effectively absorbed to H pylori. Immunohistochemical studies of the absorbed sera showed no decrease of antigastric autoreactivity. Pathogenic mechanisms other than molecular mimicry lead to the formation of antigastric autoantibodies, and epitopes other than Lewis antigens are the autoimmune targets.<\/jats:p>","DOI":"10.1136\/jcp.51.3.244","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T19:05:02Z","timestamp":1230750302000},"page":"244-245","source":"Crossref","is-referenced-by-count":54,"title":["Evidence of novel pathogenic pathways for the formation of antigastric autoantibodies in Helicobacter pylori gastritis."],"prefix":"10.1136","volume":"51","author":[{"given":"G","family":"Faller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Steininger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Appelmelk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Kirchner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1998,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0016-5085(91)90023-E","article-title":"Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa","volume":"101","author":"Negrini, R.; Lisato, L.; Zanella, I.","year":"1991","unstructured":"Negrini R, Lisato L, Zanella I, et al. 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