{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T09:18:19Z","timestamp":1765012699406,"version":"3.46.0"},"reference-count":7,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1998,4]]},"abstract":"<jats:p>AIM: To compare throat swabs with sputum specimens for Chlamydia pneumoniae antigen detection. METHODS: During a one year period, sputum and throat swabs from 50 patients over 15 years of age with acute or persisting lower respiratory tract infection were examined for C pneumoniae antigen by direct immunofluorescence. RESULTS: C pneumoniae antigen was detected in 18\/50 patients (36.0%) from sputum, throat swab, or both. Paired sputum and throat swabs were received from 35\/50 patients (70.0%). C pneumoniae antigen was detected in either or both specimens from 14\/35 patients (40.0%). Of the 14 positive patients, both specimens were positive in nine (64.3%), throat swab only in four (28.6%), and sputum only in one (7.1%). Of the remaining 15 patients from whom only a single specimen was sent, a further three of eight throat swabs and one of seven sputum specimens were positive. There was no statistically significant difference between the results obtained from the two types of specimen. CONCLUSIONS: Throat swabs may be as good as sputum for the detection of C pneumoniae antigen.<\/jats:p>","DOI":"10.1136\/jcp.51.4.309","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T19:05:02Z","timestamp":1230750302000},"page":"309-311","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of throat swabs with sputum specimens for the detection of Chlamydia pneumoniae antigen by direct immunofluorescence."],"prefix":"10.1136","volume":"51","author":[{"given":"P","family":"Garnett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Brogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Lafong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Fox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1998,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1128\/CMR.8.4.451","article-title":"Chlamydia pneumoniae (TWAR)","volume":"8","author":"C\u2013C, Kuo; LA, Jackson; LA, Campbell","year":"1995","unstructured":"Kuo C\u2013C, Jackson LA, Campbell LA, et al. Chlamydia pneumoniae (TWAR). Clin Microbiol Rev 1995; 8:451\u201361.","journal-title":"Clin Microbiol Rev"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1017\/S0950268800059197","article-title":"Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma","volume":"117","author":"Hahn, D.L.; Anttila, T.; Saikku, P.","year":"1996","unstructured":"Hahn DL, Anttila T, Saikku P. Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma. Epidemiol Infect 1996; 117:513\u201317.","journal-title":"Epidemiol Infect"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0163-4453(95)80006-9","article-title":"Chlamydia pneumoniae: risk factors for seropositivity and association with coronary heart disease","volume":"30","author":"Mendall, M.A.; Carrington, D.; Strachan, D.","year":"1995","unstructured":"Mendall MA, Carrington D, Strachan D, et al. Chlamydia pneumoniae: risk factors for seropositivity and association with coronary heart disease. J Infect 1995;30:121\u20138.","journal-title":"J Infect"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1136\/jcp.46.4.313","article-title":"Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR","volume":"46","author":"Tong, C.Y.W.; Sillis, M.","year":"1993","unstructured":"Tong CYW, Sillis M. Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR. J Clin Pathol 1993;46:313\u201317.","journal-title":"J Clin Pathol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0163-4453(92)92130-B","article-title":"The diVerentiation of Chlamydia species by antigen detection in sputum specimens from patients with community acquired acute respiratory infection","volume":"I):","author":"Sillis, M.; White, P.; Caul, E.O.","year":"1992","unstructured":"Sillis M, White P, Caul EO, et al. The diVerentiation of Chlamydia species by antigen detection in sputum specimens from patients with community acquired acute respiratory infection. J Infect 1992;25(suppl I):77\u201386.","journal-title":"J Infect"},{"key":"ref_6","first-page":"262","article-title":"Evaluation of a microdot immunofluorescent antigen detection test for Chlamydia trachomatis","volume":"70","author":"Thompson, C.; Jones, R.; Smith, B.","year":"1994","unstructured":"Thompson C, Jones R, Smith B, et al. Evaluation of a microdot immunofluorescent antigen detection test for Chlamydia trachomatis. Genitourin Med 1994;70:262\u20134.","journal-title":"Genitourin Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1099\/00222615-46-11-959","article-title":"Diagnosis of Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease by microimmunofluorescence and ELISA","volume":"46","author":"Verkooyen, R.P.; Van Lent, N.A.; Mousavi Joulandan, S.A.","year":"1997","unstructured":"Verkooyen RP, Van Lent NA, Mousavi Joulandan SA, et al. Diagnosis of Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease by microimmunofluorescence and ELISA. J Med Microbiol 1997;46: 959\u201364.","journal-title":"J Med Microbiol"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.51.4.309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T09:13:17Z","timestamp":1765012397000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.51.4.309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,4]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1998,4,1]]},"published-print":{"date-parts":[[1998,4]]}},"alternative-id":["10.1136\/jcp.51.4.309"],"URL":"https:\/\/doi.org\/10.1136\/jcp.51.4.309","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1998,4]]}}}