{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:10:02Z","timestamp":1758906602364,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:p>A 67 year old man with myelodysplasia was admitted as an emergency with a six week history of rectal bleeding and diarrhoea. Barium enema showed an irregular polypoid filling defect in the lateral wall of the proximal rectum near the rectosigmoid junction. Histology showed this to be a granulocytic sarcoma (extramedullary granulocytic leukaemia; chloroma) infiltrating the bowel. A low index of suspicion of this lesion results in an incorrect diagnosis in many such cases. A chloroacetate esterase immunoperoxidase stain will confirm the granulocytic nature of the tumour cells.<\/jats:p>","DOI":"10.1136\/jcp.52.11.865","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T19:05:02Z","timestamp":1230750302000},"page":"865-866","source":"Crossref","is-referenced-by-count":9,"title":["Granulocytic sarcoma of the rectum: a rare complication of myelodysplasia."],"prefix":"10.1136","volume":"52","author":[{"given":"V","family":"Dabbagh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Browne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L A","family":"Parapia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J","family":"Price","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Batman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1999,11,1]]},"reference":[{"key":"ref_1","first-page":"364","article-title":"Observations of surgical anatomy in head and neck","author":"Burns, A.","unstructured":"Burns A. Observations of surgical anatomy in head and neck. Edinburgh: Thomas Royce, 1811:364\u20136."},{"issue":"17","key":"ref_2","first-page":"97","article-title":"A case of chloroma","volume":"1853","author":"King, A.","unstructured":"King A. A case of chloroma. Monthly J Med 1853;17:97.","journal-title":"Monthly J Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/0016-5085(91)90230-I","article-title":"Granulocytic sarcoma of the colon","volume":"100","author":"Catalano, M.F.; Levin, B.; Hart, R.S.","year":"1991","unstructured":"Catalano MF, Levin B, Hart RS, et al. Granulocytic sarcoma of the colon. Gastroenterology 1991;100:555\u20139.","journal-title":"Gastroenterology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1182\/blood.V49.5.705.705","article-title":"Characteristics of blast crisis in chronic granulocytic leukaemia","volume":"49","author":"Rosenthal, S.; Cannellos, G.; De Vita, V.T.","year":"1977","unstructured":"Rosenthal S, Cannellos G, De Vita VT, et al. Characteristics of blast crisis in chronic granulocytic leukaemia. Blood 1977;49:705\u201319.","journal-title":"Blood"},{"key":"ref_5","first-page":"445","article-title":"Acute abdomen due to granulocytic sarcoma of the terminal ileum","volume":"14","author":"Lugassy, G.; Gimon, Z.; Okon, E.","year":"1988","unstructured":"Lugassy G, Gimon Z, Okon E, et al. Acute abdomen due to granulocytic sarcoma of the terminal ileum. Eur J Surg Oncol 1988;14:445\u20138.","journal-title":"Eur J Surg Oncol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0009-9260(05)81752-0","article-title":"Case report: granulocytic sarcoma of the small bowel\u2014a rare presentation of leukaemia","volume":"49","author":"Rottenbery, G.T.; Thomas, B.M.","year":"1994","unstructured":"Rottenbery GT, Thomas BM. Case report: granulocytic sarcoma of the small bowel\u2014a rare presentation of leukaemia. Clin Radiol 1994;49:501\u20132.","journal-title":"Clin Radiol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1002\/1097-0142(19861215)58:12<2697::AID-CNCR2820581225>3.0.CO;2-R","article-title":"Granulocytic sarcoma in nonleukaemic patients","volume":"58","author":"Meiss, M.J.; Butler, J.J.; Osborne, B.M.","year":"1986","unstructured":"Meiss MJ, Butler JJ, Osborne BM, et al. Granulocytic sarcoma in nonleukaemic patients. Cancer 1986;58:2697\u2013 709.","journal-title":"Cancer"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.52.11.865","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:52:12Z","timestamp":1758905532000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.52.11.865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11]]},"references-count":7,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1999,11,1]]},"published-print":{"date-parts":[[1999,11]]}},"alternative-id":["10.1136\/jcp.52.11.865"],"URL":"https:\/\/doi.org\/10.1136\/jcp.52.11.865","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1999,11]]}}}