{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T17:49:55Z","timestamp":1780336195805,"version":"3.54.1"},"reference-count":14,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1999,5]]},"abstract":"<jats:p>A 24 year old male who suffered from the Wiskott-Aldrich syndrome developed intra-abdominal bleeding on two occasions. Radiological investigations showed aneurysmal dilatation of branches of the hepatic and superior mesenteric arteries. The second abdominal bleed necessitated laparotomy and the bleeding was localised to the kidneys. Right nephrectomy was performed and histological examination showed a necrotising vasculitis, mainly involving medium and small sized renal blood vessels. Steroids, immunosuppressive treatment, and control of blood pressure resulted in resolution of the vasculitic process and prevented further haemorrhage. Vasculitis and aneurysm formation are rarely described complications of Wiskott-Aldrich syndrome and may account for the life threatening haemorrhage which occurs in this condition.<\/jats:p>","DOI":"10.1136\/jcp.52.5.390","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T19:05:02Z","timestamp":1230750302000},"page":"390-392","source":"Crossref","is-referenced-by-count":24,"title":["Systemic vasculitis and aneurysm formation in the Wiskott-Aldrich syndrome."],"prefix":"10.1136","volume":"52","author":[{"given":"W G","family":"McCluggage","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D J","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R J","family":"Maxwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P K","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D R","family":"McCluskey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1999,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1542\/peds.13.2.133","article-title":"Pedigree demonstrating a sex-linked recessive condition characterised by draining ears, eczematoid dermatitis and bloody diarrhea","volume":"13","author":"Aldrich, R.A.; Steinberg, A.G.; Campbell, D.C.","year":"1954","unstructured":"Aldrich RA, Steinberg AG, Campbell DC. 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Child Nephrol Urol 1988;89:118\u201320.","journal-title":"Child Nephrol Urol"},{"key":"ref_8","first-page":"654","article-title":"Cutaneous T cell lymphoma and leukocytoclastic vasculitis in a longterm survivor of Wiskott-Aldrich syndrome","volume":"55","author":"Watson, R.D.; Gershwin, M.E.; Smithwick, E.","year":"1985","unstructured":"Watson RD, Gershwin ME, Smithwick E, et al. Cutaneous T cell lymphoma and leukocytoclastic vasculitis in a longterm survivor of Wiskott-Aldrich syndrome. Ann Allergy 1985;55:654\u20137."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/0090-1229(86)90018-8","article-title":"Pulmonary angiitis with atypical lymphoreticular infiltrates in Wiskott-Aldrich syndrome: possible relationship of lymphomatoid granulomatosis and EBV infection","volume":"41","author":"Ilowite, N.T.; Fligner, C.L.; Ochs, H.D.","year":"1986","unstructured":"Ilowite NT, Fligner CL, Ochs HD, et al. 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