{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T22:33:06Z","timestamp":1793572386833,"version":"4.5.0"},"reference-count":33,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Epidemiol Community Health"],"accepted":{"date-parts":[[2012,3,29]]},"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>To evaluate the power of abnormal resting ECG versus Rose Questionnaire angina and its additive value in predicting 10-year coronary heart disease (CHD) risk in an Iranian urban population with high prevalence of CHD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>There were 5101 subjects \u226530\u2005years (2900 women), free of CHD at baseline; they were categorised in to four groups according to their Rose Angina and ECG status for ischaemia as Rose\u2212\/ECG\u2212, Rose+\/ECG\u2212, Rose\u2212\/ECG+ and Rose+\/ECG+. HR of CHD was estimated using Cox regression analysis, given Rose\u2212\/ECG\u2212 as the reference. The authors used Akaike information criterion, C-index and integrated discrimination improvement indices to evaluate the prognostic value of ECG when would be added to Rose Questionnaire.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>During follow-up, 387 CHD events (169 women) were observed. Multivariate analysis showed a HR of 2.59 (95% CI 1.71 to 3.91) and 2.26 (1.48 to 3.44) for Rose+\/ECG\u2212 group in men and women, respectively. These figures for Rose\u2212\/ECG+ were 1.36 (0.90 to 2.05) in men and 2.09 (1.40 to 3.12) in women. There was no any interaction between Rose Questionnaire and gender to predict incident CHD, in age-adjusted analysis. Akaike information criterion, C-index and relative integrated discrimination improvement did not show any difference between models including Rose alone and Rose plus ECG to predict CHD events especially in men.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Rose Questionnaire as a simple screening tool is equally important to predict incident CHD in both genders. Adding abnormal ECG to angina did not culminate in higher risk for future CHD events.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/jech-2011-200242","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T22:31:08Z","timestamp":1335565868000},"page":"1104-1109","source":"Crossref","is-referenced-by-count":9,"title":["Does an electrocardiogram add predictive value to the rose angina questionnaire for future coronary heart disease? 10-year follow-up in a Middle East population"],"prefix":"10.1136","volume":"66","author":[{"given":"Davood","family":"Khalili","sequence":"first","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"},{"name":"Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzad","family":"Hadaegh","sequence":"additional","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noushin","family":"Fahimfar","sequence":"additional","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gita","family":"Shafiee","sequence":"additional","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhad","family":"Sheikholeslami","sequence":"additional","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Ghanbarian","sequence":"additional","affiliation":[{"name":"Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fereidoun","family":"Azizi","sequence":"additional","affiliation":[{"name":"Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,4,27]]},"reference":[{"key":"2025100300261225000_66.12.1104.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90952-5"},{"key":"2025100300261225000_66.12.1104.2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-858240"},{"key":"2025100300261225000_66.12.1104.3","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2009.038"},{"key":"2025100300261225000_66.12.1104.4","first-page":"645","article-title":"The diagnosis of ischaemic heart pain and intermittent claudication in field surveys","volume":"27","author":"Rose","year":"1962","journal-title":"Bull World Health Organ"},{"key":"2025100300261225000_66.12.1104.5","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1093\/oxfordjournals.eurheartj.a015167","article-title":"Prevalence of coronary artery disease and coronary risk factors in rural and urban populations of north India","volume":"18","author":"Singh","year":"1997","journal-title":"Eur Heart J"},{"key":"2025100300261225000_66.12.1104.6","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/oxfordjournals.aje.a112189","article-title":"Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: prevalence of coronary and hypertensive heart disease and associated risk factors","volume":"102","author":"Marmot","year":"1975","journal-title":"Am J Epidemiol"},{"key":"2025100300261225000_66.12.1104.7","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1997.0729"},{"key":"2025100300261225000_66.12.1104.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)83674-1"},{"key":"2025100300261225000_66.12.1104.9","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.28.3.381"},{"key":"2025100300261225000_66.12.1104.10","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/30.5.1009"},{"key":"2025100300261225000_66.12.1104.11","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(91)90009-X"},{"key":"2025100300261225000_66.12.1104.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(99)00007-4"},{"key":"2025100300261225000_66.12.1104.13","doi-asserted-by":"crossref","unstructured":"Feinleib M Lambert PM Zeiner-Henriksen T . 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