{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:59:41Z","timestamp":1791295181339,"version":"4.1.0"},"reference-count":42,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Epidemiol Community Health"],"accepted":{"date-parts":[[2016,5,20]]},"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Periodontopathogens antibodies have been shown to be associated with primary myocardial events, but little is known regarding their impact on major adverse events after a prior acute myocardial infarction (AMI). The present prospective study evaluates the association between antibody levels of 4 periodontopathogens and the risk of all-cause death or non-fatal myocardial infarction (MI) at 1\u2005year in 975 patients admitted for acute ST segment or non-ST segment elevation MI in French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI), a nationwide French survey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Multiserotype ELISAs were performed to assess levels of IgG and IgA against <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic>, <jats:italic>Prevotella intermedia<\/jats:italic> and <jats:italic>Tannerella forsythia<\/jats:italic>.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Adjusted HRs indicate the lack of association between IgG-anti-<jats:italic>Po. gingivalis<\/jats:italic> levels (0.96 (0.78 to 1.18)), IgA-anti-<jats:italic>Po. gingivalis<\/jats:italic> levels (1.13 (0.90 to 1.42)) and the risk of all-cause death or non-fatal MI at 1\u2005year. Additionally, no significant association was found between the occurence of an event at 1 year and immunoglobulins levels against the others periodontopathogens.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The present data indicate that circulating levels of periodontopathogens antibodies are not associated with an increased risk of major adverse events in patients with a prior AMI. Studies dealing with bacterial and clinical data are needed to assess the role of oral health in comprehensive cardiac rehabilitation programmes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/jech-2015-207043","type":"journal-article","created":{"date-parts":[[2016,6,20]],"date-time":"2016-06-20T23:03:38Z","timestamp":1466463818000},"page":"1236-1241","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Periodontopathogens antibodies and major adverse events following an acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI)"],"prefix":"10.1136","volume":"70","author":[{"given":"A","family":"Boillot","sequence":"first","affiliation":[{"name":"Department of Periodontology, Rothschild Hospital (AP-HP); UFR of Odontology, University of Paris Diderot, Paris, France"},{"name":"INSERM UMRS 011, Population-based Cohort Platform, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Range","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rothschild Hospital (AP-HP); UFR of Odontology, University of Paris Diderot, Paris, France"},{"name":"INSERM UMRS 1148, Laboratory for Vascular Translational Science, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Danchin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AP-HP, Georges Pompidou European Hospital, Paris, France"},{"name":"University of Paris-Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Kotti","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Paris (APHP), St Antoine Hospital, URC-EST, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Cosler","sequence":"additional","affiliation":[{"name":"INSERM UMRS 1148, Laboratory for Vascular Translational Science, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Czernichow","sequence":"additional","affiliation":[{"name":"INSERM UMRS 011, Population-based Cohort Platform, Villejuif, France"},{"name":"Department of Nutrition, Ambroise Par\u00e9 Hospital (AP-HP), University of Versailles Saint Quentin en Yvelines, Boulogne-Billancourt, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Meilhac","sequence":"additional","affiliation":[{"name":"INSERM UMRS 1188, Diab\u00e8te ath\u00e9rothrombose Th\u00e9rapies R\u00e9union Oc\u00e9an Indien, Sainte Clotilde, La R\u00e9union, France"},{"name":"La R\u00e9union University, Sainte Clotilde, La R\u00e9union, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Puymirat","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AP-HP, Georges Pompidou European Hospital, Paris, France"},{"name":"University of Paris-Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Zeller","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dijon University Hospital, Dijon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Tchetche","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinique Pasteur, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Bouchard","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rothschild Hospital (AP-HP); 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