{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T21:07:15Z","timestamp":1786396035918,"version":"build-2736575974"},"reference-count":30,"publisher":"BMJ","issue":"9","funder":[{"DOI":"10.13039\/501100007707","name":"INAIL","doi-asserted-by":"crossref","award":["research plan 2022\u20132024, scientific project P9O1"],"award-info":[{"award-number":["research plan 2022\u20132024, scientific project P9O1"]}],"id":[{"id":"10.13039\/501100007707","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Epidemiol Community Health"],"accepted":{"date-parts":[[2026,3,17]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In Italy, the 1992 asbestos ban prohibited all forms of asbestos production, use and importation. The epidemiological surveillance of mesothelioma mortality and incidence enabled the assessment of the ban\u2019s impact and subsequent phases in asbestos exposure patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>To estimate the effects of the ban, a quasi-Poisson generalised linear model was used to fit past asbestos consumption with mesothelioma mortality by gender, using distributed lag non-linear models and different asbestos consumption scenarios with and without ban. Mesothelioma cases in the period 1993\u20132021 were categorised based on type of asbestos exposure and economic sector of activities involved, to examine their temporal trend and geographical distributions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The avoided number of mesothelioma deaths was estimated to be between 8341 and 21\u2009981 in the period 1992\u20132020, depending on asbestos use scenario. As for incidence, 37\u2009003 cases were collected between 1993 and 2021. The causal role of direct asbestos use (mining and milling ore and processing asbestos in asbestos-cement and asbestos-textile industry) changed from 11.3% for cases between 1993 and 1996 to 3.2% in the most recent cases (2017\u20132021). Inversely, cases due to unexpected or atypical exposure to asbestos and in construction increased from 11.3% in 1993\u20131996\u2009to 17.0% in 2017\u20132021, and from 12.9% to 21.4%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The asbestos ban in Italy has produced substantial health benefits, with many deaths avoided. Countries that still use asbestos should consider evidence of the effects of asbestos bans, as well as the relationship between trends in mesothelioma cases and changing patterns of asbestos exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jech-2025-224991","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:20:31Z","timestamp":1774632031000},"page":"719-726","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Modelled effect on mesothelioma mortality of the asbestos ban in Italy and the subsequent phases of exposure"],"prefix":"10.1136","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9068-2137","authenticated-orcid":false,"given":"Alessandro","family":"Marinaccio","sequence":"first","affiliation":[{"name":"Occupational and Environmental Medicine, Epidemiology and Hygiene Department, Italian Workers' Compensation Authority (INAIL), Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Gariazzo","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Medicine, Epidemiology and Hygiene Department, Italian Workers' Compensation Authority (INAIL), Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Mensi","sequence":"additional","affiliation":[{"name":"Occupational Health Unit, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Consonni","sequence":"additional","affiliation":[{"name":"Occupational Health Unit, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmela","family":"Gioscia","sequence":"additional","affiliation":[{"name":"Valle d\u2019Aosta Health Local Unit, Aosta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrica","family":"Migliore","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Unit, AOU Citt\u00e0 della Salute e della Scienza di Torino - CPO Piemonte, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Gangemi","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Unit, AOU Citt\u00e0 della Salute e della Scienza di Torino - CPO Piemonte, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Genova","sequence":"additional","affiliation":[{"name":"Academic Oncology Unit, IRCCS Azienda Ospedaliera Metropolitana, Genoa, Liguria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Eccher","sequence":"additional","affiliation":[{"name":"Provincial Unit of Health, Hygiene and Occupational Medicine, Trento, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Murano","sequence":"additional","affiliation":[{"name":"Alto Adige Health Local Unit, Bolzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Fedeli","sequence":"additional","affiliation":[{"name":"Azienda Zero, Veneto Region, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Zabeo","sequence":"additional","affiliation":[{"name":"Azienda Zero, Veneto Region, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"D\u2019Agostin","sequence":"additional","affiliation":[{"name":"University of Trieste -Trieste General Hospitals, Clinical Unit of Occupational Medicine, Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Perduri","sequence":"additional","affiliation":[{"name":"Reggio Emilia Health Local Unit-IRCCS, Reggio Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Piro","sequence":"additional","affiliation":[{"name":"Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4326-3615","authenticated-orcid":false,"given":"Lucia","family":"Giovannetti","sequence":"additional","affiliation":[{"name":"Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1131-4286","authenticated-orcid":false,"given":"Iolanda","family":"Grappasonni","sequence":"additional","affiliation":[{"name":"School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Marche, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Stracci","sequence":"additional","affiliation":[{"name":"Department of Medicine, Public Health Section, University of Perugia, Perugia, Umbria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Cozzi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Lazio Regional Health Service, Local Health Unit Roma 1, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Staniscia","sequence":"additional","affiliation":[{"name":"Department of Medicine and Ageing Sciences, University \"Gabriele d\u2019Annunzio\" Chieti e Pescara, Chieti Scalo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Calista","sequence":"additional","affiliation":[{"name":"Molise Region Cancer Registry, Campobasso, 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Communities at high risk in the third wave of mesothelioma. In: Testa J , ed. Asbestos and Mesothelioma. Current Cancer Research. Cham: Springer, 2017. Available: https:\/\/doi.org\/10.1007\/978-3-319-53560-9_5","DOI":"10.1007\/978-3-319-53560-9_5"},{"key":"2026081002300736000_80.9.719.30","doi-asserted-by":"crossref","unstructured":"Binazzi A , Marzio D , Verardo M , et al . Asbestos Exposure and Malignant Mesothelioma in Construction Workers-Epidemiological Remarks by the Italian National Mesothelioma Registry (ReNaM). 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