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The effect of combined exposure to alcohol and tobacco seemed to be multiplicative rather than additive, a finding which is similar to that in laryngeal cancer patients. However, as there were only small numbers, only major deviations from the additive or multiplicative model for interaction would be detectable.<\/jats:p>","DOI":"10.1136\/jech.39.4.304","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T15:09:01Z","timestamp":1226502541000},"page":"304-307","source":"Crossref","is-referenced-by-count":34,"title":["Effect of combined alcohol and tobacco exposure on risk of cancer of the hypopharynx."],"prefix":"10.1136","volume":"39","author":[{"given":"J","family":"Olsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Sabroe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ipsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0021-9681(72)90006-9","article-title":"The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx","volume":"25","author":"Rothman, K.; Keller, A.","year":"1972","unstructured":"Rothman K, Keller A. 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