{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T21:26:49Z","timestamp":1764019609208,"version":"build-2065373602"},"reference-count":11,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Epidemiol Community Health"],"published-print":{"date-parts":[[1986,3]]},"abstract":"<jats:p>In the Southern Highlands of Tanzania the prevalence of endemic goitre due to iodine deficiency is in the range of 90% and hypothyroidism in the range of 50% of schoolchildren. The present study confirms these data and documents the beneficial effect of Lipiodol injections on thyroid function in children around the age of puberty compared with untreated children from the same villages. On the other hand, a decrease in the prevalence of goitre could not be shown. A beneficial effect is shown for infants of mothers who received iodine during pregnancy. It seems that this form of supplementation is sufficient for breast fed children for more than three years, even when a second child has been delivered in the meantime. In contrast, older siblings of these babies may become hypothyroid when breast feeding is stopped. The determination of thyroid autoantibodies in iodine treated and untreated children and in young adults showed no increasing prevalence of positive findings thus excluding iodine induced chronic thyroiditis at least in the young target population.<\/jats:p>","DOI":"10.1136\/jech.40.1.86","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T15:09:01Z","timestamp":1226502541000},"page":"86-91","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of goitre and hypothyroidism in Southern Tanzania: effect of iodised oil on thyroid hormone deficiency."],"prefix":"10.1136","volume":"40","author":[{"given":"W","family":"W\u00e4chter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Mvungi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C R","family":"Pickardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P C","family":"Scriba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,3,1]]},"reference":[{"key":"ref_1","first-page":"489","article-title":"The aetiology, prophylaxis and treatment of endemic goitre in Ukinga, Tanzania","volume":"42","author":"Latham, M.C.","year":"1965","unstructured":"Latham MC. The aetiology, prophylaxis and treatment of endemic goitre in Ukinga, Tanzania. East African Medical J 1965; 42: 489-501.","journal-title":"East African Medical J"},{"issue":"3","key":"ref_2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1136\/jech.39.3.263","article-title":"Iodine deficiency, hypothyroidism and endemic goitre in Southern Tanzania. A survey showing the positive effects of iodizhed oil injections by TSH determination in dried blood spots","volume":"39","author":"aWachter W; MG, Mvungi; E, Triebel","year":"1985","unstructured":"aWachter W, Mvungi MG, Triebel E, et al. Iodine deficiency, hypothyroidism and endemic goitre in Southern Tanzania. A survey showing the positive effects of iodizhed oil injections by TSH determination in dried blood spots. J Epidemiol Community Health, 1985, 39 (3) 263-270.","journal-title":"J Epidemiol Community Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1210\/jcem-57-4-859","article-title":"Thyroid hormone and immunological studies in endemic goiter","volume":"57","author":"Boukis, M.A.; Koutras, D.A.; Souvatzoglou, A.","year":"1983","unstructured":"Boukis MA, Koutras DA, Souvatzoglou A, et al. Thyroid hormone and immunological studies in endemic goiter.J Clin Endocrinol Metab 1983; 57: 859-62.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1530\/acta.0.1080055","article-title":"Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis","volume":"108","author":"Harach, H.R.; Escalante, D.A.; Onativia, A.","year":"1985","unstructured":"Harach HR, Escalante DA, Onativia A, et al. Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis. Acta Endocrinol 1985; 108: 55-60.","journal-title":"Acta Endocrinol"},{"key":"ref_5","article-title":"Iodized oil in the prevention of endemic goiter and cretinism. In: Endemic goiter and cretinism-iodine nutrition in health and disease. JB Stanbury","author":"Hetzel, B.S.; Thilly, C.H.; Fierro-Benitez, R.","year":"1980","unstructured":"Hetzel BS, Thilly CH, Fierro-Benitez R, et al. Iodized oil in the prevention of endemic goiter and cretinism. In: Endemic goiter and cretinism-iodine nutrition in health and disease. JB Stanbury, BS Hetzel, eds. New York, Chichester, Brisbane, Toronto: John Wiley and Sons Inc. 1980; 513-32."},{"key":"ref_6","first-page":"369","article-title":"Technique of endemic goitre surveys. In: Endemic goitre","volume":"44","author":"Perez, C.; Scrimshaw, N.S.; Munoz, J.A.","year":"1960","unstructured":"Perez C, Scrimshaw NS, Munoz JA. Technique of endemic goitre surveys. In: Endemic goitre. Monograph series no. 44 Geneva: World Health Organization, 1960; 369-84.","journal-title":"Monograph series"},{"key":"ref_7","first-page":"381","article-title":"Verbesserung und Qualitatskontrolle der radioimmunologischen Thyrotropin-Bestimmung","volume":"11","author":"Erhardt, F.; Marschner, I.; Pickardt, C.R.","year":"1973","unstructured":"Erhardt F, Marschner I, Pickardt CR, et al. Verbesserung und Qualitatskontrolle der radioimmunologischen Thyrotropin-Bestimmung. J Clin Chem Clin Biochem 1973; 11: 381-7.","journal-title":"J Clin Chem Clin Biochem"},{"key":"ref_8","first-page":"571","article-title":"radioimmunoassay in unextracted serum using antisera with binding optima at extreme pH ranges","volume":"18","year":"1980","unstructured":"radioimmunoassay in unextracted serum using antisera with binding optima at extreme pH ranges. J Clin Chem Clin Biochem, 1980; 18: 571-7.","journal-title":"J Clin Chem Clin Biochem"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/BF01478823","article-title":"Thyroxin-bindendes Globulin (TBG): Praparation, radioimmunologische Bestimmung und klinisch-diagnostische Bedeutung","volume":"55","author":"Horn, K.; Th, Kubiczek; Pickardt, C.R.","year":"1977","unstructured":"Horn K, Kubiczek Th, Pickardt CR, et al. Thyroxin-bindendes Globulin (TBG): Praparation, radioimmunologische Bestimmung und klinisch-diagnostische Bedeutung. Klin Wschr 1977; 55: 881-94.","journal-title":"Klin Wschr"},{"key":"ref_10","article-title":"Die Struma im Neugeborenenund Kindesalter. Stuttgart-New","author":"Heidemann, P.H.","year":"1984","unstructured":"Heidemann PH. Die Struma im Neugeborenenund Kindesalter. Stuttgart-New York: Thieme, 1984."},{"key":"ref_11","article-title":"Endemic goiter and cretinism: Continuing threats to world health","volume":"292","author":"Dunn, J.T.; Medeiros-Neto, G.A.","year":"1975","unstructured":"Dunn JT, Medeiros-Neto GA. Endemic goiter and cretinism: Continuing threats to world health. Pan American Health Organization Scientific Publication no 292, 1975.","journal-title":"Pan American Health Organization Scientific Publication"}],"container-title":["Journal of Epidemiology and Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jech.40.1.86","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T18:03:34Z","timestamp":1759514614000},"score":1,"resource":{"primary":{"URL":"https:\/\/jech.bmj.com\/lookup\/doi\/10.1136\/jech.40.1.86"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,3]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1986,3,1]]},"published-print":{"date-parts":[[1986,3]]}},"alternative-id":["10.1136\/jech.40.1.86"],"URL":"https:\/\/doi.org\/10.1136\/jech.40.1.86","relation":{},"ISSN":["0143-005X","1470-2738"],"issn-type":[{"type":"print","value":"0143-005X"},{"type":"electronic","value":"1470-2738"}],"subject":[],"published":{"date-parts":[[1986,3]]}}}