{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T19:24:53Z","timestamp":1766690693320,"version":"build-2065373602"},"reference-count":16,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Epidemiol Community Health"],"published-print":{"date-parts":[[1993,8]]},"abstract":"<jats:p>OBJECTIVE--To determine whether the distribution of ABO blood groups in women with ovarian cancer differs from that in the general population in a large, defined English region. DESIGN--Analysis of record abstracts of hospital care held in the Oxford record linkage study supplemented with data from the Oxford cancer registry. SETTING--Oxford Regional Health Authority area. SUBJECTS--A total of 1261 women who had ovarian cancer between 1968 and 1986 with ABO blood groups recorded on the Oxford Record Linkage Study and cross checked against the cancer registry comprised the study group. MEASUREMENTS AND MAIN RESULTS--The relative incidence of A:O and B:O blood groups in women with ovarian cancer were compared with the general population in the same region. Ovarian cancer was more common in women of blood group A than in others, with a relative incidence of 1.17. In particular, adenocarcinomas were the most common type of tumour and were associated with blood group A. The association was more striking in married women than in single women probably reflecting differences associated with parity. CONCLUSION--The association between ABO blood groups and ovarian cancer found in this English population is similar in size to that reported from several other populations. Childbearing is known to reduce the risk of ovarian cancer and our findings suggest that the blood group association may be most apparent in married, parous (that is, relatively low risk) women.<\/jats:p>","DOI":"10.1136\/jech.47.4.287","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T15:10:54Z","timestamp":1226502654000},"page":"287-289","source":"Crossref","is-referenced-by-count":37,"title":["Ovarian cancer and ABO blood groups."],"prefix":"10.1136","volume":"47","author":[{"given":"J","family":"Henderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Seagroatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Goldacre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1993,8,1]]},"reference":[{"key":"ref_1","article-title":"Mortality statistics by cause","author":"Office of Population Censuses and Surveys","year":"1990","unstructured":"Office of Population Censuses and Surveys. 1990 Mortality statistics by cause. London: HMSO, 1991."},{"key":"ref_2","article-title":"Population Censuses and Surveys, Cancer Research Campaign. Cancer statistics","author":"Office of","year":"1981","unstructured":"Office of Population Censuses and Surveys, Cancer Research Campaign. Cancer statistics. London: HMSO, 1981."},{"key":"ref_3","article-title":"Pinker GD (eds). Gynaecology by ten teachers","author":"Clayton, S.G.; Lewis, T.L.T.","unstructured":"Clayton SG, Lewis TLT, Pinker GD (eds). Gynaecology by ten teachers. 14th ed. London: Edward Arnold, 1985: 210.","edition":"14th ed"},{"key":"ref_4","article-title":"Population Censuses and Surveys. Cancer statistics registrations 1986","author":"Office of","year":"1991","unstructured":"Office of Population Censuses and Surveys. Cancer statistics registrations 1986. London: HMSO, 1991."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1136\/bmj.304.6840.1501","article-title":"Ovarian and cervical cancer","volume":"304","author":"Williams, C.","year":"1992","unstructured":"Williams C. Ovarian and cervical cancer. BMJ 1992; 304: 1501-4.","journal-title":"BMJ"},{"key":"ref_6","article-title":"World Health Organisation, International Agency for Research on Cancer, International Association for Cancer Research. Cancer incidence in five continents","author":"Muir, C.","year":"1987","unstructured":"Muir C, Waterhouse J, Mack T, Powell J eds. World Health Organisation, International Agency for Research on Cancer, International Association for Cancer Research. Cancer incidence in five continents. (vol 5). Lyon: International Agency for Research on Cancer, 1987."},{"key":"ref_7","first-page":"283","article-title":"Gynaecological cancers","volume-title":"RDT eds. Epidemiology of diseases","author":"Chamberlain, J.","year":"1982","unstructured":"Chamberlain J. Gynaecological cancers. In: Miller DL, Farmer RDT eds. Epidemiology of diseases. Oxford: Blackwell Scientific Publication, 1982: 283."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1136\/bmj.294.6586.1518","article-title":"Ovarian neoplasms, functional ovarian cysts, and oral contraceptives","volume":"294","author":"Vessey, M.; Metcalfe, A.; Wells, C.; McPherson, K.; Westhoff, C.; Yeates, D.","year":"1987","unstructured":"Vessey M, Metcalfe A, Wells C, McPherson K, Westhoff C, Yeates D. Ovarian neoplasms, functional ovarian cysts, and oral contraceptives. BMJ 1987; 294: 1518-20.","journal-title":"BMJ"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0090-8258(79)90111-2","article-title":"The woman at risk ofdeveloping ovarian cancer","volume":"7","author":"McGowan, L.; Parent, L.; Lender, W.; Norris, H.J.","year":"1979","unstructured":"McGowan L, Parent L, Lender W, Norris HJ. The woman at risk ofdeveloping ovarian cancer. Gynaecol Oncol 1979; 7: 325-44.","journal-title":"Gynaecol Oncol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/bjc.1991.275","article-title":"Genetic predisposition to cancer","volume":"64","author":"Ponder, B.A.","year":"1991","unstructured":"Ponder BA. Genetic predisposition to cancer. Brit J Cancer 1991; 64: 203-4.","journal-title":"Brit J Cancer"},{"key":"ref_11","first-page":"380","article-title":"The ABO blood groups in neoplastic disease of the ovary","volume":"15","author":"Osborn, R.H.; de George, F.V.","year":"1963","unstructured":"Osborn RH, de George FV. The ABO blood groups in neoplastic disease of the ovary. Am J Hum Genet 1963; 15: 380-8.","journal-title":"Am J Hum Genet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1002\/1097-0142(19840615)53:12<2746::AID-CNCR2820531235>3.0.CO;2-P","article-title":"Case-control study of ovarian cancer in Japan","volume":"53","author":"Mori, M.; Kiyosawa, H.; Miyake, H.","year":"1984","unstructured":"Mori M, Kiyosawa H, Miyake H. Case-control study of ovarian cancer in Japan. Cancer 1984; 53: 2746-52.","journal-title":"Cancer"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/ije\/13.1.15","article-title":"Blood group distribution in women with ovarian cancer","volume":"13","author":"Bjorkholm, E.","year":"1984","unstructured":"Bjorkholm E. Blood group distribution in women with ovarian cancer. Int J Epidemiol 1984; 13: 15-7.","journal-title":"Int J Epidemiol"},{"key":"ref_14","first-page":"185","article-title":"Malignant tumours of the ovary. A histological classification, epidemiological considerations and survival","volume":"95","year":"1987","unstructured":"Malignant tumours of the ovary. A histological classification, epidemiological considerations and survival. Acta Pathol Microbiol Immunol Scand 1987; 95: 185-92.","journal-title":"Acta Pathol Microbiol Immunol Scand"},{"key":"ref_15","article-title":"Blood groups and diseases","author":"Mourant, A.E.; Kopec, A.C.; Domaniewska-Sobczak, K.","year":"1978","unstructured":"Mourant AE, Kopec AC, Domaniewska-Sobczak K. Blood groups and diseases. Oxford: Oxford University Press, 1978."},{"key":"ref_16","first-page":"591","article-title":"In: Roitt IM, Delves PH eds. Encyclopedia of immunology. vol 2","author":"Smith, D.F.; antigen, Prieto P.A.Forssmann","year":"1992","unstructured":"Smith DF, Prieto PA. Forssmann antigen. In: Roitt IM, Delves PH eds. Encyclopedia of immunology. vol 2. London: Academic Press, 1992: 591-2."}],"container-title":["Journal of Epidemiology and Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jech.47.4.287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T15:26:05Z","timestamp":1759505165000},"score":1,"resource":{"primary":{"URL":"https:\/\/jech.bmj.com\/lookup\/doi\/10.1136\/jech.47.4.287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,8]]},"references-count":16,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1993,8,1]]},"published-print":{"date-parts":[[1993,8]]}},"alternative-id":["10.1136\/jech.47.4.287"],"URL":"https:\/\/doi.org\/10.1136\/jech.47.4.287","relation":{},"ISSN":["0143-005X","1470-2738"],"issn-type":[{"type":"print","value":"0143-005X"},{"type":"electronic","value":"1470-2738"}],"subject":[],"published":{"date-parts":[[1993,8]]}}}