{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T21:10:11Z","timestamp":1760735411375,"version":"build-2065373602"},"reference-count":12,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1974,9]]},"abstract":"<jats:p>A family is described in which four sibs are affected with haemoglobin H disease. To our knowledge, this is the first instance where this disorder has been encountered in the Lebanon. In fact only a few cases have so far been reported from the Arab world.<\/jats:p>\n               <jats:p>All four sibs had typical haemoglobin H bands on electrophoretic examination, and characteristic intracorpuscular inclusion bodies were demonstrated in a variable proportion of their erythrocytes, as well as in cells from a younger sib and from the mother. The latter also had elevation of the Hb-A2 fraction, and it is suggested that the above family has a combination of \u03b1- and <jats:italic>\u03b2<\/jats:italic>-thalassaemia.<\/jats:p>","DOI":"10.1136\/jmg.11.3.275","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:50:51Z","timestamp":1226328651000},"page":"275-279","source":"Crossref","is-referenced-by-count":6,"title":["Haemoglobin H disease and \u03b2-thalassaemia: Clinical haematological and electrophoretic studies in a family from South Lebanon"],"prefix":"10.1136","volume":"11","author":[{"given":"Munib J.","family":"Shahid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farid P.","family":"Khouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itaf F.","family":"Sahli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1974,9,1]]},"reference":[{"key":"ref_1","article-title":"Practical HaematologyGrune and","author":"Dacie, J.V.; Lewis, S.M.","year":"1963","unstructured":"Dacie, J. V. and Lewis, S. M. (eds) (1963). Practical Haematology, 3rd edition. Grune and Stratton, New York.","edition":"3"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/clinchem\/4.6.484","article-title":"A new method for starch gel electrophoresis of human hemoglobins, with special reference to the determination of hemoglobin A2","volume":"4","author":"Goldberg, C.A.J.","year":"1958","unstructured":"Goldberg, C. A. J. (1958). A new method for starch gel electrophoresis of human hemoglobins, with special reference to the determination of hemoglobin A2. Clinical Chemistry, 4, 484-495.","journal-title":"Clinical Chemistry"},{"key":"ref_3","first-page":"911","article-title":"Description d'une nouvelle variete d'anemie hemolytique congenitale; etude hematologique, electrophoretique et genetique. 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North-Holland, Amsterdam."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/1781055b0","article-title":"Genetic and haematological significance of haemoglobin H","volume":"178","author":"Motulsky, A.G.","year":"1956","unstructured":"Motulsky, A. G. (1956). Genetic and haematological significance of haemoglobin H. Nature, 178, 1055-1056.","journal-title":"Nature"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/223059a0","article-title":"Further evidence for a genetic basis of haemoglobin H disease from new-born offsprings of patients","volume":"223","author":"Na-Nakorn, S.; Wasi, P.; Pornpatkul, M.; Pootrakul, S.","year":"1969","unstructured":"Na-Nakorn, S., Wasi, P., Pornpatkul, M., and Pootrakul, S. (1969). Further evidence for a genetic basis of haemoglobin H disease from new-born offsprings of patients. 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