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Though there was some evidence that the variant was unstable in vitro, there was no obvious haemoglobinopathy in vivo.<\/jats:p>","DOI":"10.1136\/jmg.12.3.294","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:50:51Z","timestamp":1226328651000},"page":"294-296","source":"Crossref","is-referenced-by-count":12,"title":["Haemoglobin Hasharon in a north Italian community."],"prefix":"10.1136","volume":"12","author":[{"given":"R","family":"Alberti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G M","family":"Mariuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Marinucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Bruni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Tenteri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1975,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0006-3002(61)90490-5","article-title":"An improved method for the fingerprinting of human hemoglobin","volume":"48","author":"Baglioni, C.","year":"1961","unstructured":"Baglioni, C. (1961). An improved method for the fingerprinting of human hemoglobin. Biochimica et Biophysica Acta, 48, 392-396.","journal-title":"Biochimica et Biophysica Acta"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1365-2141.1972.tb07096.x","article-title":"A simple method for the detection of unstable haemoglobins","volume":"23","author":"Carrell, R.W.; Kay, R.","year":"1972","unstructured":"Carrell, R. W. and Kay, R. (1972). A simple method for the detection of unstable haemoglobins. British Journal of Haematology, 23, 615-619.","journal-title":"British Journal of Haematology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1172\/JCI106041","article-title":"Hemoglobin Hasharon (a2 47 His (CD5) 02): a hemoglobin found in low concentration","volume":"48","author":"Charache, S.; Mondzac, A.M.; Gessner, U.","year":"1969","unstructured":"Charache, S., Mondzac, A. M., and Gessner, U. (1969). Hemoglobin Hasharon (a2 47 His (CD5) 02): a hemoglobin found in low concentration. Journal of Clinical Investigation, 48, 834-847.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_4","article-title":"Abnormal human haemoglobins. Separation and characterization of the alpha and beta chains by chromatography, and the determination of two new variants Hb Chesapeak and Hb","author":"Clegg, J.B.; Naughton, M.A.; Weatherall, D.J.","year":"1966","unstructured":"Clegg, J. B., Naughton, M. A., and Weatherall, D. J. (1966). Abnormal human haemoglobins. Separation and characterization of the alpha and beta chains by chromatography, and the determination of two new variants Hb Chesapeak and Hb J (Bangkok)."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0304-4165(65)90147-9","article-title":"Combinations of specific color reactions useful in the peptide mapping technique","volume":"107","author":"Easley, C.W.","year":"1965","unstructured":"Easley, C. W. (1965). Combinations of specific color reactions useful in the peptide mapping technique. Biochimica et Biophysica Acta, 107, 386-388.","journal-title":"Biochimica et Biophysica Acta"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/ajcp\/39.6.567","article-title":"A rapid method for microelectrophoresis and quantitation of hemoglobins on cellulose acetate","volume":"39","author":"Graham, J.L.; Grunbaum, B.W.","year":"1963","unstructured":"Graham, J. L. and Grunbaum, B. W. (1963). A rapid method for microelectrophoresis and quantitation of hemoglobins on cellulose acetate. American Journal of Clinical Pathology, 39, 567-578.","journal-title":"American Journal of Clinical Pathology"},{"issue":"6","key":"ref_7","first-page":"827","article-title":"Hemoglobin Hasharon (alpha 47 aspartic acid-+histidine)","volume":"3","author":"Halbrecht, I.; Isaacs, W.A.; Lehmann, H.; Ben-Porat, F.","year":"1967","unstructured":"Halbrecht, I., Isaacs, W. A., Lehmann, H., and Ben-Porat, F. (1967). Hemoglobin Hasharon (alpha 47 aspartic acid-+histidine). Israel Journal of Medical Sciences, 3 (6), 827-831.","journal-title":"Israel Journal of Medical Sciences"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0022-2836(62)80012-6","article-title":"On recombination of canine and human haemoglobins","volume":"4","author":"Huehns, E.R.; Shooter, E.M.; Beaven, G.H.","year":"1962","unstructured":"Huehns, E. R., Shooter, E. M., and Beaven, G. H. (1962). On recombination of canine and human haemoglobins. Journal of Molecular Biology, 4, 323-328.","journal-title":"Journal of Molecular Biology"},{"key":"ref_9","first-page":"539","article-title":"Abnormal human haemoglobins. I. The comparison of normal human and SICKLE-cell haemoglobins by 'fingerprinting'","volume":"28","author":"Ingram, V.M.","year":"1958","unstructured":"Ingram, V. M. (1958). Abnormal human haemoglobins. I. The comparison of normal human and SICKLE-cell haemoglobins by 'fingerprinting'. Biochimica et Biophysica Acta, 28, 539-545.","journal-title":"Biochimica et Biophysica Acta"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1172\/JCI106421","article-title":"The role of hemoglobin heme loss in Heinz body formation: studies with a partially heme-deficient hemoglobin and with genetically unstable hemoglobins","volume":"49","author":"Jacob, H.S.; Winterhalter, K.H.","year":"1970","unstructured":"Jacob, H. S. and Winterhalter, K. H. (1970). The role of hemoglobin heme loss in Heinz body formation: studies with a partially heme-deficient hemoglobin and with genetically unstable hemoglobins. Journal of Clinical Investigation, 49, 2008-2016.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/ajcp\/58.5.428","article-title":"Separation of globin chains by rapid cellulose acetate electrophoresis","volume":"58","author":"Komarmy, L.; Barnes, M.G.","year":"1972","unstructured":"Komarmy, L. and Barnes, M. G. (1972). Separation of globin chains by rapid cellulose acetate electrophoresis. American Journal of Clinical Pathology, 58, 428-430.","journal-title":"American Journal of Clinical Pathology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0006-3002(58)90108-2","article-title":"Studies on the structure of hemoglobin. I. Physicochemical properties of human globin","volume":"30","author":"Rossi-Fanelli, A.; Antonini, E.; Caputo, A.","year":"1958","unstructured":"Rossi-Fanelli, A., Antonini, E., and Caputo, A. (1958). Studies on the structure of hemoglobin. I. Physicochemical properties of human globin. Biochimica et Biophysica Acta, 30, 608-615.","journal-title":"Biochimica et Biophysica Acta"},{"key":"ref_13","first-page":"47","article-title":"His beta2): a new variant in a Jewish family","volume":"2","author":"Schneider, R.G.; Ueda, S.; Alperin, J.B.; Brisnhall, B.; Jones, R.T.","year":"1968","unstructured":"Schneider, R. G., Ueda, S., Alperin, J. B., Brisnhall, B., and Jones, R. T. (1968). Hemoglobin Sealy (alpha2 47 His beta2): a new variant in a Jewish family. 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