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The normal haematological findings in the patient's parents, as well as their blood groups and isozymes, suggest that the occurrence of her Hb M Hyde Park was the result of a fresh mutation.<\/jats:p>","DOI":"10.1136\/jmg.13.2.142","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:50:51Z","timestamp":1226328651000},"page":"142-147","source":"Crossref","is-referenced-by-count":11,"title":["Haemoglobin M Hyde Park occurring as a fresh mutation: diagnostic, structural, and genetic considerations."],"prefix":"10.1136","volume":"13","author":[{"given":"G","family":"Stamatoyannopoulos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P E","family":"Nute","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Giblett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Detter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Chard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1976,4,1]]},"reference":[{"issue":"37","key":"ref_1","article-title":"Abnormal human hemoglobins. 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D., and Yakulis, V. J. (1966). Structural studies of haemoglobin M Hyde Park. In Proceedings of the 11th Congress of the International Society of Blood Transfusion, Sydney, Part 4, pp. 1073-1084."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0022-2836(62)80012-6","article-title":"On the recombination of canine and human haemoglobins","volume":"4","author":"Huehns, E.R.; Shooter, E.M.; Beaven, G.H.","year":"1962","unstructured":"Huehns, E. R., Shooter, E. M., and Beaven, G. H. (1962). On the recombination of canine and human haemoglobins. Journal of Molecular Biology, 4, 323-328.","journal-title":"Journal of Molecular Biology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1073\/pnas.65.3.697","article-title":"Unstable hemoglobins: the role of heme loss in Heinz body formation","volume":"65","author":"Jacob, H.; Winterhalter, K.","year":"1970","unstructured":"Jacob, H. and Winterhalter, K. (1970). 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