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The implications of the finding of this marker chromosome on amniocentesis, believed to be reported for the first time here, are discussed particularly in the context of genetic counselling.<\/jats:p>","DOI":"10.1136\/jmg.15.2.136","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:50:51Z","timestamp":1226328651000},"page":"136-142","source":"Crossref","is-referenced-by-count":24,"title":["Significance of detection of extra metacentric microchromosome in amniotic cell culture."],"prefix":"10.1136","volume":"15","author":[{"given":"R","family":"Bernstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Hakim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Hardwick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G T","family":"Nurse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1978,4,1]]},"reference":[{"key":"ref_1","first-page":"25","article-title":"The syndrome of the metacentric microchromosome","author":"Abbo, G.; Zellweger, H.","year":"1970","unstructured":"Abbo, G., and Zellweger, H. 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