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This prerequisite was presumptively established in the single kindred analysed because acrocephalosyndactyly was observed in multiple cases in multiple generations.<\/jats:p>","DOI":"10.1136\/jmg.15.4.292","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:50:51Z","timestamp":1226328651000},"page":"292-293","source":"Crossref","is-referenced-by-count":6,"title":["Linkage analysis in dominant acrocephalosyndactyly."],"prefix":"10.1136","volume":"15","author":[{"given":"J R","family":"Eastman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Escobar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Bixler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1978,8,1]]},"reference":[{"key":"ref_1","first-page":"791","article-title":"Zum entwichlungsmechanischen Problem der Akrocephalosyndaktylie. 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