{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:01:06Z","timestamp":1761058866245,"version":"build-2065373602"},"reference-count":13,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1983,2]]},"abstract":"<jats:p>Three deaths from dissection of the aorta in a series of 157 adult women with Turner's syndrome are reported. These are greatly in excess of the numbers expected. None of the three patients had a coarctation of the aorta. One had aortic regurgitation but there was no reason to believe that the aorta in the other two patients had been subjected to unusual haemodynamic stresses. Cystic medial necrosis of the aorta was described in two patients on whom necropsies were carried out. It is concluded that there is probably a greatly increased risk of dissection of the aorta in Turner's syndrome even in the absence of any other abnormality of the aorta and aortic valve. Previously reported cases of aortic dissection in Turner's syndrome are discussed.<\/jats:p>","DOI":"10.1136\/jmg.20.1.61","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:52:06Z","timestamp":1226328726000},"page":"61-63","source":"Crossref","is-referenced-by-count":41,"title":["Dissection of the aorta in Turner's syndrome."],"prefix":"10.1136","volume":"20","author":[{"given":"W H","family":"Price","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,2,1]]},"reference":[{"key":"ref_1","first-page":"193","article-title":"Sindrome de Turner: comunicacion de un caso asociado con aneurisma disecante de la aorta","volume":"19","author":"Salgado, C.R.","year":"1961","unstructured":"Salgado CR. Sindrome de Turner: comunicacion de un caso asociado con aneurisma disecante de la aorta. Rev Fac Ciene Med Cordoba 1961;19:193-204.","journal-title":"Rev Fac Ciene Med Cordoba"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0022-5223(19)33503-2","article-title":"Dissecting aneurysm of aorta associated with Turner's syndrome","volume":"47","author":"Anabtawi, I.N.; Ellison, R.G.; Yeh, T.J.; Hall, D.P.","year":"1964","unstructured":"Anabtawi IN, Ellison RG, Yeh TJ, Hall DP. Dissecting aneurysm of aorta associated with Turner's syndrome. J Thorac Cardiovasc Surg 1964;47:750-4.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0002-9149(69)90246-X","article-title":"Aneurysm of the aortic sinuses and ascending aorta in Turner's syndrome","volume":"23","author":"Youker, J.E.; Benson, B.R.","year":"1969","unstructured":"Youker JE, Benson BR. Aneurysm of the aortic sinuses and ascending aorta in Turner's syndrome. Amn J Cardiol 1969;23:89-93.","journal-title":"Amn J Cardiol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/0002-9343(65)90014-8","article-title":"Ulirich-Turner syndrome associated with cystic medial necrosis of the aorta and great vessels","volume":"38","author":"Kostich, N.D.; Opitz, J.M.","year":"1965","unstructured":"Kostich ND, Opitz JM. Ulirich-Turner syndrome associated with cystic medial necrosis of the aorta and great vessels. Am J Med 1965;38:943-9.","journal-title":"Am J Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1001\/jama.1972.03210050046010","article-title":"Dissecting aneurysm of the aorta in Turner's syndrome","volume":"222","author":"Jeresaty, R.M.; Subrata, K.B.; Franco, J.","year":"1972","unstructured":"Jeresaty RM, Subrata KB, Franco J. Dissecting aneurysm of the aorta in Turner's syndrome. 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Am Heart J 1947;33: 146-52.","journal-title":"Am Heart J"},{"key":"ref_8","first-page":"1","article-title":"Dissecting aneurysms of the aorta in persons under 40 years of age","volume":"55","author":"Gore, I.","year":"1953","unstructured":"Gore I. Dissecting aneurysms of the aorta in persons under 40 years of age. Arch Pathol 1953;55:1-14.","journal-title":"Arch Pathol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1161\/01.CIR.16.2.188","article-title":"Association of aortic valvular disease and cystic medial necrosis of the ascending aorta","volume":"46","author":"McKusick, V.A.; Logue, R.B.; Bahnson, H.T.","year":"1957","unstructured":"McKusick VA, Logue RB, Bahnson HT. Association of aortic valvular disease and cystic medial necrosis of the ascending aorta. Circiulation 1957;46:188-91.","journal-title":"Circiulation"},{"key":"ref_10","article-title":"Heritable disorders of connective tissue","author":"McKusick, V.A.","year":"1972","unstructured":"McKusick VA. Heritable disorders of connective tissue. 3rd ed. St Louis: Mosby, 1972.","edition":"3rd ed"},{"key":"ref_11","first-page":"77","article-title":"The biosynthesis of collagen and its disorders","volume":"301","author":"Prockop, D.N.; Kivivkko, K.I.; Tuderman, L.; Guzman, N.A.","year":"1981","unstructured":"Prockop DN, Kivivkko KI, Tuderman L, Guzman NA. The biosynthesis of collagen and its disorders. N Engl J Med 1981;301:77-85.","journal-title":"N Engl J Med"},{"issue":"1","key":"ref_12","first-page":"19","article-title":"Le syndrome du pterygium; status Bonnevie-Ullrich, dystrophia brevicollis congenita, syndrome de Turner et arthromyodysplasia congenita","volume":"6","author":"Rossi, E.; Caflisch, A.","year":"1951","unstructured":"Rossi E, Caflisch A. 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Helv PaediatrActa 1951;6:245-54.","journal-title":"Helv PaediatrActa"}],"container-title":["Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jmg.20.1.61","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T17:51:01Z","timestamp":1759686661000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmg.bmj.com\/lookup\/doi\/10.1136\/jmg.20.1.61"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,2]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1983,2,1]]},"published-print":{"date-parts":[[1983,2]]}},"alternative-id":["10.1136\/jmg.20.1.61"],"URL":"https:\/\/doi.org\/10.1136\/jmg.20.1.61","relation":{},"ISSN":["0022-2593","1468-6244"],"issn-type":[{"type":"print","value":"0022-2593"},{"type":"electronic","value":"1468-6244"}],"subject":[],"published":{"date-parts":[[1983,2]]}}}