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In addition, we report that antibodies capable of stimulating the thyroid were detectable in the sputum of both the patient and his mother.<\/jats:p>","DOI":"10.1136\/jmg.20.2.133","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:52:06Z","timestamp":1226328726000},"page":"133-134","source":"Crossref","is-referenced-by-count":1,"title":["Graves' disease and Down's syndrome"],"prefix":"10.1136","volume":"20","author":[{"given":"A J","family":"McCulloch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N R","family":"Steele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1136\/jmg.19.3.232","article-title":"Autoimmune chronic active hepatitis in Down's syndrome","volume":"19","author":"McCulloch, A.J.; Ince, P.; Kendall-Taylor, P.","year":"1982","unstructured":"McCulloch AJ, Ince P, Kendall-Taylor P. 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Lancet 1977;ii: 163-6.","journal-title":"Lancet"},{"key":"ref_6","first-page":"293","article-title":"Immunity in Down's syndrome","volume":"127","author":"Burgio, G.R.; Ugazio, A.G.","year":"1978","unstructured":"Burgio GR, Ugazio AG. Immunity in Down's syndrome. EurJPediatr 1978;127:293-4.","journal-title":"EurJPediatr"},{"key":"ref_7","first-page":"237","article-title":"Immune characteristics of Down's syndrome","volume":"21","author":"Gershwin, M.E.; Crinella, F.M.; Castles, J.J.; Trent, J.K.T.","year":"1977","unstructured":"Gershwin ME, Crinella FM, Castles JJ, Trent JKT. Immune characteristics of Down's syndrome. J Ment Defic Res 1977;21:237-49.","journal-title":"J Ment Defic Res"},{"key":"ref_8","first-page":"76","article-title":"Familial predisposition to thyroid disease in Down's syndrome: controlled immunoclinical studies","volume":"23","author":"Fialkow, P.J.; Thuline, H.C.; Hecht, F.; Bryant, J.","year":"1971","unstructured":"Fialkow PJ, Thuline HC, Hecht F, Bryant J. Familial predisposition to thyroid disease in Down's syndrome: controlled immunoclinical studies. Am J Hum Genet 1971;23:76-86.","journal-title":"Am J Hum Genet"}],"container-title":["Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jmg.20.2.133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T04:56:23Z","timestamp":1760763383000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmg.bmj.com\/lookup\/doi\/10.1136\/jmg.20.2.133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1983,4,1]]},"published-print":{"date-parts":[[1983,4]]}},"alternative-id":["10.1136\/jmg.20.2.133"],"URL":"https:\/\/doi.org\/10.1136\/jmg.20.2.133","relation":{},"ISSN":["0022-2593","1468-6244"],"issn-type":[{"type":"print","value":"0022-2593"},{"type":"electronic","value":"1468-6244"}],"subject":[],"published":{"date-parts":[[1983,4]]}}}