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The patient and several members of her family showed decreased activities of erythrocyte NADH-cytochrome b5 reductase, predisposing them to the development of clinically significant methaemoglobinaemia when challenged with oxidant drugs.<\/jats:p>","DOI":"10.1136\/jmg.20.4.307","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:52:06Z","timestamp":1226328726000},"page":"307-309","source":"Crossref","is-referenced-by-count":12,"title":["Phenazopyridine induced methaemoglobinaemia associated with decreased activity of erythrocyte cytochrome b5 reductase."],"prefix":"10.1136","volume":"20","author":[{"given":"J S","family":"Daly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D E","family":"Hultquist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D L","family":"Rucknagel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1001\/jama.1951.03670010028007","article-title":"Methemoglobinemia associated with pyridium administration; report of a case","volume":"146","author":"Crawford, S.E.; HE, Jr, Moon; Panos, T.C.; Hooks, C.A.","year":"1951","unstructured":"Crawford SE, Moon HE Jr, Panos TC, Hooks CA. 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