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There was a much higher rate of renal and urinary tract defects in the Bristol series, and a higher rate of cardiovascular defects in the Lancashire series. The distribution of associated malformations differed in the two areas, possibly representing different patterns of aetiological heterogeneity. The iniencephaly rate was so much lower in Lancashire as to suggest an artefact, perhaps owing to the lack of a precise definition of the condition.<\/jats:p>","DOI":"10.1136\/jmg.20.5.338","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T14:52:06Z","timestamp":1226328726000},"page":"338-341","source":"Crossref","is-referenced-by-count":10,"title":["Congenital malformations associated with anencephaly in the Fylde peninsula of Lancashire."],"prefix":"10.1136","volume":"20","author":[{"given":"T J","family":"David","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F C","family":"McCrae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J P","family":"Bound","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/jmg.12.1.1","article-title":"Oesophageal atresia in the South West of England","volume":"12","author":"David, T.J.; O'Callaghan, S.E.","year":"1975","unstructured":"David TJ, O'Callaghan SE. 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