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It is suggested that in all pregnancies, regardless of the predicted outcome, the biochemical status of carrier mothers should be monitored because hyperammonaemia and arginine deficiency may have a deleterious effect on the fetus.<\/jats:p>","DOI":"10.1136\/jmg.22.6.462","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:09:16Z","timestamp":1226329756000},"page":"462-465","source":"Crossref","is-referenced-by-count":13,"title":["Prenatal diagnosis of ornithine carbamoyl transferase deficiency using a gene specific probe."],"prefix":"10.1136","volume":"22","author":[{"given":"M E","family":"Pembrey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Old","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J V","family":"Leonard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C H","family":"Rodeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Warren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K E","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,12,1]]},"reference":[{"issue":"8","key":"ref_1","first-page":"5","article-title":"Metabolic and genetic studies of a family with ornithine transcarbamylase deficiency","volume":"1974","author":"Goldstein, A.S.; Hoogenraad, N.J.; Johnson, J.D.","unstructured":"Goldstein AS, Hoogenraad NJ, Johnson JD, et al. 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