{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T18:40:28Z","timestamp":1759689628175,"version":"build-2065373602"},"reference-count":12,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1987,10]]},"abstract":"<jats:p>The relationship between parental constitutional chromosome abnormalities and the development of hydatidiform mole was evaluated in series from four institutions. Karyotype analysis was performed on blood samples from 237 patients with a pathological diagnosis of complete mole and 217 of their spouses. One patient was found to have a constitutional balanced translocation, t(11;18), while one spouse was found to have a balanced translocation, t(4;20). Among 125 patients with partial mole and 106 of their spouses, one male was found to be a translocation carrier, t(13;14). No significant increase in the frequency of translocations in the parents of complete moles was found in any of the series considered separately or together. Data from the combined series show no evidence of constitutional parental chromosome aberrations as an aetiological factor in the development of molar pregnancies.<\/jats:p>","DOI":"10.1136\/jmg.24.10.613","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:09:16Z","timestamp":1226329756000},"page":"613-615","source":"Crossref","is-referenced-by-count":11,"title":["Hydatidiform mole: parental chromosome aberrations in partial and complete moles."],"prefix":"10.1136","volume":"24","author":[{"given":"L O","family":"Vejerslev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Surti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Wake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1987,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/268633a0","article-title":"Androgenetic origin of hydatidiform mole","volume":"268","author":"Kajii, T.; Ohama, K.","year":"1977","unstructured":"Kajii T, Ohama K. Androgenetic origin of hydatidiform mole. Nature 1977;268:633-4.","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/jnci\/60.1.51","article-title":"Androgenesis as a cause of hydatidiform mole","volume":"60","author":"Wake, N.; Takagi, N.; Sasaki, M.","year":"1978","unstructured":"Wake N, Takagi N, Sasaki M. Androgenesis as a cause of hydatidiform mole. J Natl Cancer Inst 1978;60:51-7.","journal-title":"J Natl Cancer Inst"},{"key":"ref_3","first-page":"580","article-title":"Genetic studies of complete and partial hydatidiform moles","volume":"ii:","author":"Lawler, S.D.; Pickthall, V.J.; Fisher, R.A.; Povey, S.; Wyn Evans, M.; Szulman, A.E.","year":"1979","unstructured":"Lawler SD, Pickthall VJ, Fisher RA, Povey S, Wyn Evans M, Szulman AE. Genetic studies of complete and partial hydatidiform moles. 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Morphologic evolution of the complete and partial mole","volume":"132","author":"Szulman, A.E.; Surti, U.","year":"1978","unstructured":"Szulman AE, Surti U. The syndromes of hydatidiform mole. II. Morphologic evolution of the complete and partial mole. Am J Obstet Gynecol 1978;132:20-7.","journal-title":"Am J Obstet Gynecol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1469-1809.1980.tb01556.x","article-title":"A G-band study of chromosomes in liveborn infants","volume":"43","author":"Buckton, K.; O'Riordan, M.L.; Ratcliffe, S.; Slight, J.; Mitchell, M.; McBeath, S.","year":"1980","unstructured":"Buckton K, O'Riordan ML, Ratcliffe S, Slight J, Mitchell M, McBeath S. A G-band study of chromosomes in liveborn infants. 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Gestational trophoblastic diseases","year":"1983","unstructured":"Report of a WHO Scientific Group. Gestational trophoblastic diseases. WHO Technical Report Series 1983;692."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/j.1471-0528.1985.tb03069.x","article-title":"Recurrent pregnancy losses and parental chromosome abnormalities: a review","volume":"92","author":"Tharapel, A.T.; Tharapel, S.A.; Bannerman, R.M.","year":"1985","unstructured":"Tharapel AT, Tharapel SA, Bannerman RM. Recurrent pregnancy losses and parental chromosome abnormalities: a review. Br J Obstet Gynaecol 1985;92:899-914.","journal-title":"Br J Obstet Gynaecol"}],"container-title":["Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jmg.24.10.613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T18:04:37Z","timestamp":1759687477000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmg.bmj.com\/lookup\/doi\/10.1136\/jmg.24.10.613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,10]]},"references-count":12,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1987,10,1]]},"published-print":{"date-parts":[[1987,10]]}},"alternative-id":["10.1136\/jmg.24.10.613"],"URL":"https:\/\/doi.org\/10.1136\/jmg.24.10.613","relation":{},"ISSN":["0022-2593","1468-6244"],"issn-type":[{"type":"print","value":"0022-2593"},{"type":"electronic","value":"1468-6244"}],"subject":[],"published":{"date-parts":[[1987,10]]}}}