{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:01:06Z","timestamp":1761058866353,"version":"build-2065373602"},"reference-count":12,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1988,8]]},"abstract":"<jats:p>Ectrodactyly of the feet has been reported only twice in association with trisomy 18 syndrome. A severe form of this anomaly, the first with published illustrative x rays, is described in a male infant with trisomy 18 syndrome. It is suggested that this may represent an extreme expression of the foot anomalies more commonly associated with this syndrome.<\/jats:p>","DOI":"10.1136\/jmg.25.8.568","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"568-570","source":"Crossref","is-referenced-by-count":10,"title":["Trisomy 18 syndrome with cleft foot."],"prefix":"10.1136","volume":"25","author":[{"given":"D","family":"Castle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1988,8,1]]},"reference":[{"key":"ref_1","article-title":"Recognizable patterns of human malformations","author":"Smith, D.W.","year":"1982","unstructured":"Smith DW. Recognizable patterns of human malformations. Philadelphia: Saunders, 1982."},{"key":"ref_2","first-page":"628","article-title":"Catalogue of unbalanced chromosome aberrations in man","author":"Schinzel, A.","year":"1983","unstructured":"Schinzel A. Catalogue of unbalanced chromosome aberrations in man. Berlin: Walter de Gruyter, 1983:628-33."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1136\/adc.40.214.600","article-title":"E(16-18) trisomy syndrome: analysis of 13 cases","volume":"40","author":"Butler, L.J.; Snodgrass, G.J.A.I.; France, N.E.; Sinclair, L.; Russell, A.","year":"1965","unstructured":"Butler LJ, Snodgrass GJAI, France NE, Sinclair L, Russell A. E(16-18) trisomy syndrome: analysis of 13 cases. 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J Med Genet 1984;21:293-7.","journal-title":"J Med Genet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/ajmg.1320020309","article-title":"Anatomical analysis of the developmental effects of aneuploidy in man-the 18-trisomy syndrome. II. Anomalies of the upper and lower limbs","volume":"3","author":"Ramirez-Castro, J.L.; Bersu, E.T.","year":"1978","unstructured":"Ramirez-Castro JL, Bersu ET. Anatomical analysis of the developmental effects of aneuploidy in man-the 18-trisomy syndrome. II. Anomalies of the upper and lower limbs. Am J Med Genet 1978;3:285-306.","journal-title":"Am J Med Genet"},{"key":"ref_7","first-page":"36","article-title":"The genetics of hand malformations","author":"Temtamy, S.; McKusick, V.","year":"1978","unstructured":"Temtamy S, McKusick V. The genetics of hand malformations. New York: Alan R Liss, 1978:36-71."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1136\/jmg.24.4.220","article-title":"Ectrodactyly in sisters and half sisters","volume":"24","author":"Mufti, M.H.; Wood, S.K.","year":"1987","unstructured":"Mufti MH, Wood SK. Ectrodactyly in sisters and half sisters. J Med Genet 1987;24:220-4.","journal-title":"J Med Genet"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/ajmg.1320190317","article-title":"The split-hand and split-foot anomaly in a Central African Negro population","volume":"19","author":"Viljoen, D.L.; Beighton, P.","year":"1984","unstructured":"Viljoen DL, Beighton P. The split-hand and split-foot anomaly in a Central African Negro population. Am J Med Genet 1984;19:545-52.","journal-title":"Am J Med Genet"},{"key":"ref_10","unstructured":"Correspondence and requests for reprints to Dr Renee Bernstein, Department of Human Genetics, South African Institute for Medical Research, PO Box 1038, Johannesburg 2000, South Africa.","article-title":"Correspondence and requests for reprints to Dr Renee Bernstein"},{"key":"ref_11","unstructured":"Deletion of band 5q21 in association with a de novo translocation involving 2p and 5q","article-title":"Deletion of band 5q21 in association with a de novo translocation involving 2p and 5q"},{"article-title":"Revised version accepted for publication","year":"1987","key":"ref_12","unstructured":"Revised version accepted for publication 7 August 1987."}],"container-title":["Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jmg.25.8.568","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T19:50:17Z","timestamp":1760730617000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmg.bmj.com\/lookup\/doi\/10.1136\/jmg.25.8.568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,8]]},"references-count":12,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1988,8,1]]},"published-print":{"date-parts":[[1988,8]]}},"alternative-id":["10.1136\/jmg.25.8.568"],"URL":"https:\/\/doi.org\/10.1136\/jmg.25.8.568","relation":{},"ISSN":["0022-2593","1468-6244"],"issn-type":[{"type":"print","value":"0022-2593"},{"type":"electronic","value":"1468-6244"}],"subject":[],"published":{"date-parts":[[1988,8]]}}}