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This occurred after coinheritance of alpha+ thalassaemia and APKD, which resulted in an altered band size for the (+) RsaI restriction fragment length polymorphism.<\/jats:p>","DOI":"10.1136\/jmg.26.1.6","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"6-9","source":"Crossref","is-referenced-by-count":1,"title":["Alpha thalassaemia: a potential source of error in DNA linkage studies for adult polycystic kidney disease."],"prefix":"10.1136","volume":"26","author":[{"given":"R J","family":"Trent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R C","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1989,1,1]]},"reference":[{"key":"ref_1","first-page":"540","article-title":"A highly polymorphic DNA marker is linked to adult polycystic kidney disease on chromosome 16","volume":"317","author":"Reeders, S.T.; Breuning, M.H.; Davies, K.E.","year":"1985","unstructured":"Reeders ST, Breuning MH, Davies KE, et al. 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'o","volume":"12","author":"Assum, G.; Griese, E.U.; Horst, J.","year":"1984","unstructured":"Assum G, Griese EU, Horst J. Detection of a restriction site polymorphism within the human a-globin gene complex. Hum Genet 1985;69:144-6. 'o Higgs DR, Hill AVS, Bowden DK, Weatherall DJ, Clegg JB. Independent recombination events between the duplicated human a globin genes: implications for their concerted evolution. Nucleic Acids Res 1984;12:6965-77. 2' Nicholls RD, Fischel-Ghodsian N, Higgs DR. Recombination at ihe human a globin gene cluster: sequence features and topological constraints. 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