{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:07:53Z","timestamp":1761718073881,"version":"build-2065373602"},"reference-count":16,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1989,10]]},"abstract":"<jats:p>A unique case of de novo interstitial deletion of chromosome 4 is described involving loss of band q21. The male newborn had multiple abnormalities including frontal bossing, prominent occiput, low set ears, micrognathia, short sternum, short, broad hands and feet, agenesis of the corpus callosum, and cardiac defects. The phenotypic abnormalities are compared with other reported cases of deletion 4q involving adjacent regions.<\/jats:p>","DOI":"10.1136\/jmg.26.10.644","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"644-647","source":"Crossref","is-referenced-by-count":11,"title":["A new interstitial deletion of 4q (q21.1::q22.1)."],"prefix":"10.1136","volume":"26","author":[{"given":"K","family":"Fagan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1989,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/BF00401233","article-title":"Tentative assignment of piebald trait gene to chromosome band 4ql2","volume":"73","author":"Hoo, J.J.; Haslam, R.H.; van Oram, C.","year":"1986","unstructured":"Hoo JJ, Haslam RH, van Oram C. 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