{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:45:55Z","timestamp":1787931955749,"version":"build-2784847793"},"reference-count":11,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1990,2]]},"abstract":"<jats:p>We report two male sibs and two female sibs from separate families, both with normal parents, who had a lethal condition with features of the Yunis-Varon syndrome and radiological signs of severe osteodysplasty. Autosomal recessive inheritance is likely in both families. The additional features described represent further delineation of the phenotype of the Yunis-Varon syndrome.<\/jats:p>","DOI":"10.1136\/jmg.27.2.114","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"114-121","source":"Crossref","is-referenced-by-count":24,"title":["Yunis-Varon syndrome with severe osteodysplasty."],"prefix":"10.1136","volume":"27","author":[{"given":"C","family":"Garrett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A C","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R H","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1990,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1136\/jmg.26.1.55","article-title":"Further delineation of the Yunis-Varon syndrome","volume":"21","author":"Hennekam, R.C.M.; Vermeulen-Meiners, C.","year":"1989","unstructured":"Hennekam RCM, Vermeulen-Meiners C. Further delineation of the Yunis-Varon syndrome. J Med Genet 1989;21:55-8.","journal-title":"J Med Genet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1001\/archpedi.1980.02130190017005","article-title":"Cleidocranial dysostosis, severe micrognathism, bilateral absence of thumbs and first metatarsal bones and distal aphalangia","volume":"134","author":"Yunis, E.; Varon, H.","year":"1980","unstructured":"Yunis E, Varon H. Cleidocranial dysostosis, severe micrognathism, bilateral absence of thumbs and first metatarsal bones and distal aphalangia. Am Jf Dis Child 1980;134:649-53.","journal-title":"Am Jf Dis Child"},{"key":"ref_3","first-page":"171","article-title":"Precocious type of osteodysplasia. A new autosomal recessive form","volume":"14","author":"Kozlowski, K.; Mayne, V.; Danks, D.M.","year":"1973","unstructured":"Kozlowski K, Mayne V, Danks DM. Precocious type of osteodysplasia. A new autosomal recessive form. 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Congenital malformations associated with osteodysplasty. A new malformations complex. Acta Radiol [Diagn] (Stockh) 1981;22:369-77.","journal-title":"Acta Radiol [Diagn] (Stockh)"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/ajmg.1320130416","article-title":"Omphalocele and multiple severe congenital anomalies associated with osteodysplasty (Melnick-Needies syndrome)","volume":"13","author":"P, Von Oeyen; LB, Holmes; RL, Trelstad; NT, Griscom","year":"1982","unstructured":"Von Oeyen P, Holmes LB, Trelstad RL, Griscom NT. Omphalocele and multiple severe congenital anomalies associated with osteodysplasty (Melnick-Needies syndrome). 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