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In all those affected by the disease, a fragile site on the long arm of chromosome 16 was found, expressed with different frequencies, but the unaffected family members did not show this trait.<\/jats:p>","DOI":"10.1136\/jmg.27.6.363","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"363-366","source":"Crossref","is-referenced-by-count":8,"title":["Cosegregation of hypertrophic cardiomyopathy and a fragile site on chromosome 16 in a large Italian family."],"prefix":"10.1136","volume":"27","author":[{"given":"M","family":"Ferraro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Scarton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Ambrosini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1990,6,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM197310042891402","article-title":"Familial prevalence and genetic -transmission of idiopathic hypertrophic subaortic stenosis","volume":"289","author":"Clark, C.E.; Henry, W.L.; Epstein, S.E.","year":"1973","unstructured":"Clark CE, Henry WL, Epstein SE. 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