{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T01:55:11Z","timestamp":1767664511582,"version":"build-2065373602"},"reference-count":14,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Genet"],"published-print":{"date-parts":[[1990,6]]},"abstract":"<jats:p>A pterygium, a wing-like thickening, of the bulbar conjunctiva is of environmental interest because it can occur on prolonged exposure to wind and weather. We describe a family with pterygium in two generations without a history of unusual exposure to the elements. There were six females and five males (including a set of male twins) with seven bilateral and four unilateral pterygia. The onset was unique in being in early adulthood, from the late teens through the twenties. This new genetic form can be distinguished by the age of onset from congenital and mid-adult pterygia, which are inherited as autosomal dominant traits. Irrespective of age, the treatment of conjunctival pterygium is surgical excision.<\/jats:p>","DOI":"10.1136\/jmg.27.6.392","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:11:11Z","timestamp":1226329871000},"page":"392-394","source":"Crossref","is-referenced-by-count":27,"title":["Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva."],"prefix":"10.1136","volume":"27","author":[{"given":"F","family":"Hecht","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Shoptaugh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1990,6,1]]},"reference":[{"key":"ref_1","unstructured":"Congenital pterygium Conjunctival pterygium can occur at any age. Congenital pterygium is rare but has been reported by Jacklin' in 1964 in six members (four females, two males) in a three generation kindred. Murken and Table 2 Environmental factors thought to play a role in pterygium of the conjunctiva and cornea.","article-title":"Congenital pterygium Conjunctival pterygium can occur at any age. Congenital pterygium is rare but has been reported by Jacklin' in 1964 in six members (four females, two males) in a three generation kindred. Murken and Table 2 Environmental factors thought to play a role in pterygium of the conjunctiva and cornea"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/0002-9394(64)92668-6","article-title":"Familial predisposition to pterygium formation: report of a family","volume":"57","author":"HN, I.Jacklin","year":"1964","unstructured":"I Jacklin HN. Familial predisposition to pterygium formation: report of a family. AmJ Ophthalmol 1964;57:481-2.","journal-title":"AmJ Ophthalmol"},{"key":"ref_3","first-page":"574","article-title":"Zur Genetik des Pterygium corneae","volume":"147","author":"Murken, J.D.; Dannheim, R.","year":"1965","unstructured":"Murken JD, Dannheim R. Zur Genetik des Pterygium corneae. Klin Monatsbl Augenheilkd 1965;147:574-9.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"ref_4","article-title":"Mendelian inheritance in man","author":"McKusick, V.A.","year":"1988","unstructured":"McKusick VA. Mendelian inheritance in man. Baltimore: Johns Hopkins University Press, 1988."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1755-3768.1987.tb07016.x","article-title":"An investigation of aetiology and heredity of pterygium. Report of 11 cases in a family","volume":"65","author":"Zhang, J.-D.","year":"1987","unstructured":"Zhang J-D. An investigation of aetiology and heredity of pterygium. Report of 11 cases in a family. Acta Ophthalmol (Copenh) 1987;65:413-6.","journal-title":"Acta Ophthalmol (Copenh)"},{"issue":"91","key":"ref_6","first-page":"267","article-title":"Genetics and ophthalmology. Vol 1","volume":"1","author":"Waardenburg, J.P.","unstructured":"Waardenburg JP. Genetics and ophthalmology. Vol 1. Assen: Royal VanGorcum, 1%91:267-8."},{"issue":"50","key":"ref_7","first-page":"635","article-title":"Pterygium: its incidence, heredity and etiology","volume":"1960","author":"Hilgers, J.H.C.","unstructured":"Hilgers JHC. Pterygium: its incidence, heredity and etiology. AmJ Ophthalmol 1960;50:635-44.","journal-title":"AmJ Ophthalmol"},{"key":"ref_8","first-page":"573","volume":"8","author":"ofophthalmology, Duke-Elder S.System","unstructured":"Duke-Elder S. System ofophthalmology. Vol 8. London: Kimpton, 1%5:573-85."},{"key":"ref_9","first-page":"786","volume":"4","author":"ophthalmology, Sorsby AModern","year":"1972","unstructured":"Sorsby A, ed. Modern ophthalmology. Vol 4. London: Butterworths, 1972:786-8."},{"key":"ref_10","first-page":"179","article-title":"Investigation on etiology of the pterygium","volume":"13","author":"Qi, X.Z.","year":"1966","unstructured":"Qi XZ. Investigation on etiology of the pterygium. Zhonghua Yanke Zazhi 1966;13:179-82.","journal-title":"Zhonghua Yanke Zazhi"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0002-9394(67)93353-3","article-title":"The role of environmental factors in cataract, pterygium and trachoma","volume":"64","author":"Dhir, S.P.; Detels, R.; Alexander, E.R.","year":"1967","unstructured":"Dhir SP, Detels R, Alexander ER. The role of environmental factors in cataract, pterygium and trachoma. Am3J Ophthalmol 1967;64: 128-35.","journal-title":"Am3J Ophthalmol"},{"key":"ref_12","first-page":"102","article-title":"Solar keratosis pterygium, and squamous cell carcinoma of the conjunctiva in Malawi. Br J7 Ophthalmol","volume":"63","author":"Chirambo, M.C.; Hutt, M.S.R.","year":"1979","unstructured":"Chirambo MC, Hutt MSR. Solar keratosis pterygium, and squamous cell carcinoma of the conjunctiva in Malawi. Br J7 Ophthalmol 1979;63:102-9."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1136\/bjo.64.3.154","article-title":"Aetiology of climatic droplet keratopathy and pterygium","volume":"64","author":"Tarlor, H.R.","year":"1980","unstructured":"Tarlor HR. Aetiology of climatic droplet keratopathy and pterygium. BrJ Ophthalmol 1980;64:154-63.","journal-title":"BrJ Ophthalmol"},{"key":"ref_14","first-page":"469","article-title":"Familial hypersensitivity to insect stings","volume":"ii:","author":"Hecht, F.","year":"1971","unstructured":"Hecht F. Familial hypersensitivity to insect stings. Lancet 1971;ii:469.","journal-title":"Lancet"}],"container-title":["Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jmg.27.6.392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T04:20:52Z","timestamp":1759724452000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmg.bmj.com\/lookup\/doi\/10.1136\/jmg.27.6.392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,6]]},"references-count":14,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1990,6,1]]},"published-print":{"date-parts":[[1990,6]]}},"alternative-id":["10.1136\/jmg.27.6.392"],"URL":"https:\/\/doi.org\/10.1136\/jmg.27.6.392","relation":{},"ISSN":["0022-2593","1468-6244"],"issn-type":[{"type":"print","value":"0022-2593"},{"type":"electronic","value":"1468-6244"}],"subject":[],"published":{"date-parts":[[1990,6]]}}}