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From early childhood, structural failure of the bone resulted in the disruption of growth plates, progressive bone deformities, and severe growth retardation.<\/jats:p>","DOI":"10.1136\/jmg.33.11.968","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:37:21Z","timestamp":1226331441000},"page":"968-971","source":"Crossref","is-referenced-by-count":9,"title":["Disrupted growth plates and progressive deformities in osteogenesis imperfecta as a result of the substitution of glycine 585 by valine in the alpha 2 (I) chain of type I collagen."],"prefix":"10.1136","volume":"33","author":[{"given":"W G","family":"Cole","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C W","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J G","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"Bateman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1996,11,1]]},"reference":[{"issue":"16","key":"ref_1","first-page":"101","article-title":"Genetic heterogeneity in osteogenesis imperfecta..7 Med","volume":"1979","author":"Sillence, D.O.; Senn, A.; Danks, D.M.","unstructured":"Sillence DO, Senn A, Danks DM. 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