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It is suggested that there may be more than one gene involved in the aetiology of this syndrome, particularly as the very rare families in which more than one girl is affected often show variable clinical symptoms.<\/jats:p>","DOI":"10.1136\/jmg.35.12.997","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T15:37:21Z","timestamp":1226331441000},"page":"997-1003","source":"Crossref","is-referenced-by-count":40,"title":["Linkage analysis in Rett syndrome families suggests that there may be a critical region at Xq28."],"prefix":"10.1136","volume":"35","author":[{"given":"T","family":"Webb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Hanefeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Rosenbloom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C G","family":"Woods","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1998,12,1]]},"reference":[{"issue":"3","key":"ref_1","first-page":"506","article-title":"The clinical recognition and differential diagnosis of Rett syndrome","volume":"1988","author":"Trevathan, E.; Naidu, S.","unstructured":"Trevathan E, Naidu S. 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