{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:12:29Z","timestamp":1760782349542,"version":"build-2065373602"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Med Genet"],"accepted":{"date-parts":[[2000,11,6]]},"published-print":{"date-parts":[[2001,1,1]]},"abstract":"<jats:p>The moral aspects of genetic counselling are explored in situations where the outcome of a DNA test does not lead to certain knowledge. The most frequent type of interaction between counsellor and counsellee is when factual information is given, but sometimes \u201cfactual\u201d information is difficult to obtain. How do counsellors deal with \u201cuncertain\u201d knowledge in genetics? Arguments and assumptions are presented and the finding of a 27 CAG repeat in the Huntington gene is used as an example. However, the questions \u201chow far does the duty to inform reach?\u201d and \u201cto what extent is the doctor responsible?\u201d are important in the whole field of genetics, and will be even more important in the future. The aims of science and clinical practice are discussed; we conclude that counsellors run the risk of taking on an infinite responsibility.<\/jats:p>","DOI":"10.1136\/jmg.38.1.39","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T06:38:40Z","timestamp":1027751920000},"page":"39-42","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["The whole truth and nothing but the truth, but what is the truth?"],"prefix":"10.1136","volume":"38","author":[{"given":"Hanneke M A van den Boer-van","family":"den Berg","sequence":"first","affiliation":[{"name":"aDepartment of Clinical Genetics, Erasmus University Medical Centre, PO Box 23435, 3001 KK Rotterdam, The Netherlands, \n\nbDepartments of Philosophy, Medical Ethics, and History of Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands, \n\ncDepartment of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anneke A","family":"Maat-Kievit","sequence":"additional","affiliation":[{"name":"aDepartment of Clinical Genetics, Erasmus University Medical Centre, PO Box 23435, 3001 KK Rotterdam, The Netherlands, \n\nbDepartments of Philosophy, Medical Ethics, and History of Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands, \n\ncDepartment of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2001,1,1]]},"reference":[{"key":"2025101713194590000_38.1.39.1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90585-E"},{"key":"2025101713194590000_38.1.39.2","first-page":"A246","article-title":"Evidence of an unstable paternal 27 CAG repeat allele in the huntingtin gene giving rise to clinically overt Huntington disease in a patient with the genotype (17\/38).","volume":"57","author":"McGlennan","year":"1995","journal-title":"Am J Hum Genet Suppl"},{"key":"2025101713194590000_38.1.39.3","unstructured":"Maat-Kievit JA, Losekoot M, van den Boer-van den Berg JMA, van Ommen GJ, Breuning M, Tibben A. 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