{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:43:15Z","timestamp":1787240595713,"version":"build-2736575974"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1999,3,1]],"date-time":"1999-03-01T00:00:00Z","timestamp":920246400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[1999,3,1]]},"abstract":"<jats:p\/>\n                  <jats:p>Objectives To determine the prevalence of haemoglobinopathies and the need for neonatal screening for haemoglobinopathies in Brussels.<\/jats:p>\n                  <jats:p>Methods Between December 1994 and June 1998 23 136 cord blood samples obtained in eight hospital nurseries of Brussels were systematically screened for haemoglobinopathies by isoelectric focusing.<\/jats:p>\n                  <jats:p>Results 45% of the newborns were from regions at risk for haemoglobinopathies. Sickle cell disease was diagnosed for 11 neonates (0.048%) and \u03b2 thalassaemia major for one neonate. Three hundred and fifty neonates (1.5%) were carriers for a haemoglobin variant, and Hb Bart's was found in 672 cases (2.9%). These prevalences are similar to those reported elsewhere in northern Europe.<\/jats:p>\n                  <jats:p>Conclusions These results confirm the value of universal screening for haemoglobinopathies in Brussels.<\/jats:p>","DOI":"10.1136\/jms.6.1.11","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T12:32:20Z","timestamp":1369917140000},"page":"11-15","source":"Crossref","is-referenced-by-count":21,"title":["Newborn screening for haemoglobinopathies: the Brussels experience"],"prefix":"10.1177","volume":"6","author":[{"given":"B.","family":"Gulbis","sequence":"first","affiliation":[{"name":"Department of Clinical Chemistry, H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Tshilolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Cotton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Vertongen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1999,3,1]]},"container-title":["Journal of Medical Screening"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1136\/jms.6.1.11","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1136\/jms.6.1.11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:50:17Z","timestamp":1777614617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1136\/jms.6.1.11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,3,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,3,1]]}},"alternative-id":["10.1136\/jms.6.1.11"],"URL":"https:\/\/doi.org\/10.1136\/jms.6.1.11","relation":{},"ISSN":["0969-1413","1475-5793"],"issn-type":[{"value":"0969-1413","type":"print"},{"value":"1475-5793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,3,1]]}}}