{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T21:54:34Z","timestamp":1776376474463,"version":"3.51.2"},"reference-count":30,"publisher":"BMJ","issue":"e3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2022,12,14]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients with end-stage renal disease (ESRD) are often excluded from clinical trials of endovascular thrombectomy (EVT). This study investigated the outcome in these patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>From September 2014 to July 2021, all patients undergoing EVT for anterior circulation stroke in two stroke centers in Taiwan were included. They were divided into no renal dysfunction (non-RD, estimated glomerular filtration rate (eGFR) \u226560 mL\/min\/1.73 m<jats:sup>2<\/jats:sup>), RD (eGFR &lt;60 mL\/min\/1.73 m<jats:sup>2<\/jats:sup> but no dialysis), and ESRD undergoing dialysis (ESRD-dialysis). The clinical features and outcomes were compared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 482 patients included, there were 20 ESRD-dialysis, 110 RD, and 352 non-RD patients. The Alberta Stroke Program Early CT Score (ASPECTS), National Institutes of Health Stroke Scale (NIHSS), use of intravenous thrombolysis, EVT-related time metrics, and successful recanalization rates were comparable among the three groups. However, the ESRD-dialysis patients had more symptomatic intracerebral hemorrhage (ICH, 15% vs 3.6% vs 3.7%), more contrast-induced encephalopathy (15% vs 1.8% vs 0.9%), and a higher mortality at 90 days (35% vs 18% vs 11%) than the other groups. Multivariable analysis revealed that ESRD-dialysis was associated with a less favorable outcome (OR 0.21, 95% CI 0.04 to 0.77) and more severe disability or mortality (modified Rankin Scale 5 or 6; OR 13.1, 95% CI 3.93 to 48.1) at 90 days. In the ESRD-dialysis group, the patients with premorbid functional dependence had a significantly higher mortality than those without (75% vs 8.3%; P=0.004).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>ESRD-dialysis patients were associated with symptomatic ICH and less favorable outcome at 90 days. Patients with premorbid functional dependency had an excessively high mortality.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/jnis-2022-019666","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:20:46Z","timestamp":1671542446000},"page":"e337-e342","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Outcome of endovascular thrombectomy in patients with end-stage renal disease undergoing dialysis"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8867-1615","authenticated-orcid":false,"given":"Kuo-Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Surgery, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1258-8775","authenticated-orcid":false,"given":"Chih-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Taipei, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4327-7432","authenticated-orcid":false,"given":"Yen-Heng","family":"Lin","sequence":"additional","affiliation":[{"name":"Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Wei","family":"Lee","sequence":"additional","affiliation":[{"name":"Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun-Chang","family":"Tsai","sequence":"additional","affiliation":[{"name":"Neurology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Kai","family":"Tsai","sequence":"additional","affiliation":[{"name":"Neurology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Chun","family":"Tang","sequence":"additional","affiliation":[{"name":"Neurology, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1456-3686","authenticated-orcid":false,"given":"Jiann-Shing","family":"Jeng","sequence":"additional","affiliation":[{"name":"Neurology, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,20]]},"reference":[{"key":"2025092912010743000_15.e3.e337.1","doi-asserted-by":"crossref","first-page":"e328","DOI":"10.1161\/STROKEAHA.120.029680","article-title":"Chronic 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