{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:04:16Z","timestamp":1789380256212,"version":"build-2803163510"},"reference-count":10,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2025,10,13]]},"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the technical feasibility, safety, and short-term to mid-term efficacy of the antithrombogenic-coated CARESTO stent in the endovascular treatment of acute symptomatic cervical internal carotid artery dissections (CICAD) with hemodynamically relevant stenosis and disabling neurological deficits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective multicenter study evaluated patients with acute symptomatic CICAD who underwent endovascular treatment with the CARESTO stent. Clinical endpoints included changes in the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS) scores. Imaging endpoints assessed vessel patency, arterial diameter improvement, and revascularization success, defined as a modified Thrombolysis in Cerebral Infarction (mTICI) score \u22652b. Safety was evaluated by documenting periprocedural complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between January 2023 and May 2025, 31 patients were treated across six participating neurovascular centers. The mean age was 52.3\u00b110.2 years; 54.8% were female. Stent deployment was successful in all cases. In those with intracranial vessel occlusion (n=22), recanalization was achieved in all patients (mTICI 3: 61.3%; mTICI 2c: 22.6%; mTICI 2b: 16.1%). ICA diameter improved from 1.0\u00b10.5\u2009mm to 4.6\u00b10.6\u2009mm. Median NIHSS score decreased from 11 (IQR 8\u201314.5) to 1 (IQR 1\u20133) at 3 months; mRS\u22642 was achieved in 83.9%. All stents remained patent, with no major complications or deaths.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This initial multicenter experience suggests that the CARESTO stent is technically feasible and may offer a safe and effective treatment option for acute CICAD. These findings support further prospective evaluation in larger cohorts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jnis-2025-024193","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:10:17Z","timestamp":1761984617000},"page":"1971-1976","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Initial experience with the antithrombogenic-coated CARESTO stent for acute symptomatic cervical internal carotid artery dissections: multicenter study"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4233-8048","authenticated-orcid":false,"given":"Mohammad","family":"Almohammad","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3028-0539","authenticated-orcid":false,"given":"Peter B","family":"Sporns","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Basel, Basel, Switzerland"},{"name":"Department of Radiology and Neuroradiology, Stadtspital Z\u00fcrich Triemli, Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Broocks","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, HELIOS Medical Center, Campus of MSH Medical School Hamburg, Schwerin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike Peter","family":"Wattjes","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"khanafer","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Klinikum Stuttgart Katharinenhospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mete","family":"Dadak","sequence":"additional","affiliation":[{"name":"Department of Radiology, St Vincenz Hospital Paderborn, Paderborn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayan Alhaj","family":"Moustafa","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0779-0688","authenticated-orcid":false,"given":"Tawfik","family":"Moher Alsady","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Radiology and Neuroradiology, Rh\u00f6n Klinikum Campus Bad Neustadt, Bad Neustadt an der Saale, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Aburub","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Hekers","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Timmermann","sequence":"additional","affiliation":[{"name":"Department of Neurology, Philipps-University Marburg, Marburg, Germany"},{"name":"Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Gerstner","sequence":"additional","affiliation":[{"name":"Department of Neurology, Philipps-University Marburg, Marburg, Germany"},{"name":"Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Philipps-University Marburg, Marburg, Germany"},{"name":"Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Eckey","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Neuroradiology, Sch\u00f6n Klinik Neurstadt, Neustadt in Holstein, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Kemmling","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany"},{"name":"Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"},{"name":"Department of Radiology and Neuroradiology, Rh\u00f6n Klinikum Campus Bad Neustadt, Bad Neustadt an der Saale, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"2026091402151531000_18.10.1971.1","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1212\/01.wnl.0000237341.30854.6a","article-title":"Gender differences in spontaneous cervical artery dissection","volume":"67","author":"Arnold","year":"2006","journal-title":"Neurology (ECronicon)"},{"key":"2026091402151531000_18.10.1971.2","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s00234-021-02842-4","article-title":"The potential role of diffusion weighted imaging in the diagnosis of early carotid and vertebral artery 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Comparison of pEGASUS-HPC and CREDO Heal stent systems deployed via NeuroSpeed percutaneous angioplasty balloon catheter for treatment of acute symptomatic intracranial stenosis and occlusion. Clin Neuroradiol 2025. doi:10.1007\/s00062-025-01544-1","DOI":"10.1007\/s00062-025-01544-1"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnis-2025-024193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:16:08Z","timestamp":1789377368000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/jnis-2025-024193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":10,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,9,14]]},"published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1136\/jnis-2025-024193"],"URL":"https:\/\/doi.org\/10.1136\/jnis-2025-024193","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,31]]}}}