{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:08:42Z","timestamp":1790356122756,"version":"4.1.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2026,4,27]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Venous sinus stenting (VSS) is an established treatment for patients with idiopathic intracranial hypertension (IIH). However, the associated effect of VSS on skull base remodeling has not been described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a single center retrospective study of adults with symptomatic venous sinus stenosis who underwent VSS. Tegmen (tympani and mastoideum) volume was measured on thin cut cranial CT using semi-automated 3D Slicer segmentation. The primary outcome was the within patient change in tegmen volume before and after VSS. Paired analyses were performed for the overall cohort and right-sided stent subgroups. Multivariable linear regression was used to identify factors associated with bilateral tegmen volume change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 65 patients treated with VSS from 2022 to 2026, 25 met the inclusion criteria. Mean age was 40.4 years, 92.0% were women, and median imaging follow-up was 295 days. Inter-rater reproducibility was excellent for the volumetric analysis on predefined anatomical segmentation boundaries. Four surgically repaired right-sided skull base patients were excluded from the ipsilateral analysis. Significant post-stenting mean tegmen growth was observed: right 146\u2009mm\u00b3 (95%\u2009CI 118 to 174; n=21; P&lt;0.001), left 145\u2009mm\u00b3 (95%\u2009CI 114 to 170; n=25; P&lt;0.001), and bilateral total 299\u2009mm\u00b3 (95%\u2009CI 250 to 348; n=21; P&lt;0.001). In the right-sided stent cohort, both ipsilateral and contralateral tegmen volumes increased significantly. Longer follow-up duration and pulsatile tinnitus were independently associated with bilateral tegmen volume gain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VSS was associated with a significant bilateral increase in tegmen volume in patients with IIH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jnis-2026-025367","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:20:42Z","timestamp":1778779242000},"page":"jnis-2026-025367","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Venous sinus stent placement is associated with improvement in volumetric skull base thickness"],"prefix":"10.1136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6882-9339","authenticated-orcid":false,"given":"Siddharth","family":"Srinivasan","sequence":"first","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6425-8472","authenticated-orcid":false,"given":"Lauren","family":"Benck","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3387-0360","authenticated-orcid":false,"given":"Brett","family":"Thorell","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8662-3588","authenticated-orcid":false,"given":"Vishnu Achyuth","family":"Suresh","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Borg","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E","family":"Surdell","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William E","family":"Thorell","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Casazza","sequence":"additional","affiliation":[{"name":"Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mithun","family":"Sattur","sequence":"additional","affiliation":[{"name":"Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"2026051410202864000_jnis-2026-025367v1.1","doi-asserted-by":"crossref","first-page":"e490","DOI":"10.1097\/WNO.0000000000001118","article-title":"Prediction of Postoperative Risk of Raised Intracranial Pressure After Spontaneous Skull Base Cerebrospinal Fluid Leak Repair","volume":"41","author":"Buchowicz","year":"2021","journal-title":"J Neuroophthalmol"},{"key":"2026051410202864000_jnis-2026-025367v1.2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816630738"},{"key":"2026051410202864000_jnis-2026-025367v1.3","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2003.43"},{"key":"2026051410202864000_jnis-2026-025367v1.4","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000001504"},{"key":"2026051410202864000_jnis-2026-025367v1.5","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002249"},{"key":"2026051410202864000_jnis-2026-025367v1.6","doi-asserted-by":"crossref","DOI":"10.1177\/15910199241311626","article-title":"Venous sinus stenting for management of spontaneous skull-base CSF leaks: A systematic review and meta-analysis","volume":"PubMed Central PMCID","author":"Rasmussen","year":"2025","journal-title":"Interv Neuroradiol"},{"key":"2026051410202864000_jnis-2026-025367v1.7","doi-asserted-by":"publisher","DOI":"10.1227\/neu.0000000000002718"},{"key":"2026051410202864000_jnis-2026-025367v1.8","doi-asserted-by":"crossref","unstructured":"Srinivasan S , Patel K , Surdell DL , et al . Enabling Minimal Access for Middle Cranial Fossa Cerebrospinal Fluid Leak Repair via Optimal Craniotomy Centering: A Cadaveric Morphometric Study. J Neurol Surg B Skull Base 2026. doi:10.1055\/a-2805-6554","DOI":"10.1055\/a-2805-6554"},{"key":"2026051410202864000_jnis-2026-025367v1.9","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2020-016636"},{"key":"2026051410202864000_jnis-2026-025367v1.10","first-page":"jnis","article-title":"Sigmoid plate dehiscence regrowth following transverse sinus stenting for pulsatile tinnitus","volume":"PubMed PMID","author":"Klein","year":"2026","journal-title":"J Neurointervent Surg"},{"key":"2026051410202864000_jnis-2026-025367v1.11","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/MOO.0b013e328011bc76","article-title":"Evaluation of spontaneous nasal cerebrospinal fluid leaks","volume":"15","author":"Wise","year":"2007","journal-title":"Curr Opin Otolaryngol Head Neck Surg"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnis-2026-025367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:20:44Z","timestamp":1778779244000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/jnis-2026-025367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,14]]},"references-count":11,"alternative-id":["10.1136\/jnis-2026-025367"],"URL":"https:\/\/doi.org\/10.1136\/jnis-2026-025367","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,14]]}}}