{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:14:53Z","timestamp":1773087293678,"version":"3.50.1"},"reference-count":18,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J NeuroIntervent Surg"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to determine whether the timing of carotid artery stenting (CAS) affects peri-procedural outcomes in recently symptomatic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Early carotid endarterectomy following a stroke lowers the risk of recurrent ischemic events but has been associated with an increased risk of intracerebral hemorrhage. The optimal timing of CAS following a stroke is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using a single-center prospective CAS registry, we retrospectively analyzed data on consecutive CAS procedures over an 8-year period. Patients were separated into early (\u22644\u2005weeks) and late (&gt;4\u2005weeks) treatment groups based on time to CAS from symptom onset. Post-procedural hypertension was treated. Thirty-day incidence of stroke, intracerebral hemorrhage, myocardial infarction and death were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 224 patients were treated for symptomatic lesions. The mean age was 71\u00b110 years, and 63% were men. The median time for CAS was 8\u2005days (0.2\u201330\u2005days) and 90\u2005days (31\u2013180\u2005days) respectively, for the early (n=122) and late (n=102) intervention groups. There were 4 (3.45%) periprocedural strokes in the early and 5 (5.95%) in the late CAS group (p=0.5). There was one hyperperfusion syndrome in each group. The 30-day stroke, myocardial infarction or death rates were similar between the early (6.03%) and late (8.33%) CAS groups, p=0.58. A multivariate analysis showed that age &gt;80\u2005years rather than timing of CAS was associated with adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CAS may be performed safely immediately following non-disabling strokes. Octogenarians may be at higher risk of complications.<\/jats:p><\/jats:sec>","DOI":"10.1136\/jnis.2009.000901","type":"journal-article","created":{"date-parts":[[2009,10,31]],"date-time":"2009-10-31T00:35:16Z","timestamp":1256949316000},"page":"55-58","source":"Crossref","is-referenced-by-count":15,"title":["The impact of timing on outcomes of carotid artery stenting in recently symptomatic 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