{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T20:27:54Z","timestamp":1759177674779},"reference-count":22,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2009,10,23]]},"published-print":{"date-parts":[[2010,6]]},"abstract":"Background and purpose<\/jats:title>Basilar artery occlusion remains one of the most devastating subtypes of stroke. Intravenous and intra-arterial therapy have altered the natural history of this disease; however, clinical results remain poor. Therefore, exploring more aggressive and innovative management is warranted.<\/jats:p><\/jats:sec>Methods<\/jats:title>Six consecutive patients presenting with a basilar artery occlusion were treated with the same general algorithm of intra-arterial tissue plasminogen activator and mechanical thrombectomy with the Merci retrieval system. If complete recanalization was not achieved after two passes, manual syringe aspiration through a 4.3F catheter was employed.<\/jats:p><\/jats:sec>Results<\/jats:title>All interventions utilizing aspiration thrombectomy resulted in recanalization, with five out of six cases displaying TIMI3\/TICI3 flow and one patient resulting in complete recanalization of the basilar artery with persistent thrombus in one P2 segment (TIMI2\/TICI2B). All patients survived, with five out of six independent in activities of daily living at 3\u2005months (mRS 0\u20132).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Our small case series indicates that aspiration thrombectomy performed manually through a 4.3F catheter can facilitate recanalization of basilar artery occlusion with acceptable clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1136\/jnis.2009.001420","type":"journal-article","created":{"date-parts":[[2010,6,16]],"date-time":"2010-06-16T20:30:29Z","timestamp":1276720229000},"page":"110-114","source":"Crossref","is-referenced-by-count":23,"title":["Endovascular treatment of basilar artery occlusion by manual aspiration thrombectomy"],"prefix":"10.1136","volume":"2","author":[{"given":"Brian T","family":"Jankowitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aitziber","family":"Aleu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ridwan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mouhammad","family":"Jumaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilal","family":"Kanaan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean","family":"Kostov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxim","family":"Hammer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Uchino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry R","family":"Wechsler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Horowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tudor G","family":"Jovin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,5,27]]},"reference":[{"key":"2024052222421558000_2.2.110.1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/69.2.73"},{"key":"2024052222421558000_2.2.110.2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.526566"},{"key":"2024052222421558000_2.2.110.3","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000202582.29510.6b"},{"key":"2024052222421558000_2.2.110.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.8.1135"},{"key":"2024052222421558000_2.2.110.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000237069.89438.a9"},{"key":"2024052222421558000_2.2.110.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.03.028"},{"key":"2024052222421558000_2.2.110.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.15.1862"},{"key":"2024052222421558000_2.2.110.8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000257304.21967.ba"},{"key":"2024052222421558000_2.2.110.9","first-page":"3","article-title":"Neuroradiologic evaluation of patients with acute stroke treated with recombinant tissue plasminogen activator. The rt-pa acute stroke study group","volume":"14","author":"Wolpert","year":"1993","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222421558000_2.2.110.10","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1110"},{"key":"2024052222421558000_2.2.110.11","unstructured":"http:\/\/www.concentric-medical.com\/webpage.php?ln_id=122. 2009."},{"key":"2024052222421558000_2.2.110.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000082721.62796.09"},{"key":"2024052222421558000_2.2.110.13","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1161\/01.CIR.73.2.338","article-title":"Intravenous recombinant tissue-type plasminogen activator in patients with acute myocardial infarction: a report from the nhlbi thrombolysis in myocardial infarction trial","volume":"73","author":"Williams","year":"1986","journal-title":"Circulation"},{"key":"2024052222421558000_2.2.110.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000258355.23810.c6"},{"key":"2024052222421558000_2.2.110.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.04.057"},{"key":"2024052222421558000_2.2.110.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)01041-6"},{"key":"2024052222421558000_2.2.110.17","first-page":"783","article-title":"Intraarterial suction thrombectomy in acute stroke","volume":"23","author":"Lutsep","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222421558000_2.2.110.18","first-page":"1521","article-title":"Clot removal therapy by aspiration and extraction for acute embolic carotid occlusion","volume":"27","author":"Imai","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222421558000_2.2.110.19","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-004-1217-z"},{"key":"2024052222421558000_2.2.110.20","first-page":"282","article-title":"Thromboaspiration in the basilar artery: report of two cases","volume":"23","author":"Chapot","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222421558000_2.2.110.21","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.544957"},{"key":"2024052222421558000_2.2.110.22","unstructured":"Rubiera MCL Patterson DE Sykes P . Diagnostic criteria and yield of real time doppler monitoring of intra-arterial procedures. International Stroke Conference, San Diego, CA. 2009."}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnis.2009.001420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T06:25:57Z","timestamp":1716445557000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/jnis.2009.001420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,27]]},"references-count":22,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2010,5,27]]},"published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1136\/jnis.2009.001420"],"URL":"https:\/\/doi.org\/10.1136\/jnis.2009.001420","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,27]]}}}