{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:14:04Z","timestamp":1787062444940,"version":"build-2736575974"},"reference-count":9,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2010,1,4]]},"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>Symptomatic intracranial atherosclerosis has been associated with a high rate of recurrent stroke. The safety of treatment of more distal atheromatous lesions with angioplasty has not been systematically reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed our institutional database for all patients treated with intracranial angioplasty and stenting from January 2008 to July 2009. A total of 108 patients were treated and five patients were treated with angioplasty for a symptomatic M2 middle cerebral artery stenosis with fluctuating neurological examinations. We report our experience with these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All five patients underwent technically successful treatment with a reduction of the stenosis to &lt;50%. There were no periprocedural complications and all patients had cessation of their clinical fluctuations. Two patients were found to have symptomatic restenosis with one patient suffering a disabling stroke at 5\u2005months and the second patient a transient ischemic attack at 4\u2005months who was subsequently successfully re-treated with angioplasty and stent placement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Angioplasty of M2 MCA lesions is technically feasible in our cohort of neurologically unstable patients, but the durability of this treatment will require more extensive study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jnis.2009.001818","type":"journal-article","created":{"date-parts":[[2010,6,4]],"date-time":"2010-06-04T20:26:22Z","timestamp":1275683182000},"page":"192-194","source":"Crossref","is-referenced-by-count":1,"title":["Initial experience with angioplasty of symptomatic M2 MCA atheromatous lesions"],"prefix":"10.1136","volume":"2","author":[{"given":"Muhammad Shazam","family":"Hussain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"Cheng-Ching","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Bain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro M","family":"Spiotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thinesh","family":"Sivapatham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaye I","family":"Moskowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2010,6,4]]},"reference":[{"key":"2024052222434602000_2.3.192.1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1161\/01.STR.26.1.14","article-title":"Race-ethnicity and determinants of intracranial atherosclerotic cerebral infarction: The Northern Manhattan Stroke Study","volume":"26","author":"Sacco","year":"1995","journal-title":"Stroke"},{"key":"2024052222434602000_2.3.192.2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000206142.03677.c2"},{"key":"2024052222434602000_2.3.192.3","doi-asserted-by":"crossref","first-page":"582","DOI":"10.3171\/2009.8.JNS09446","article-title":"Balloon angioplasty of the A(2) segment of the anterior cerebral artery for recurrent, symptomatic atherosclerotic disease","volume":"112","author":"Karakis","year":"2010","journal-title":"J Neurosurg"},{"key":"2024052222434602000_2.3.192.4","first-page":"16","article-title":"Anterior cerebral artery angioplasty for intracranial atherosclerosis","volume":"1","author":"Janjua","year":"2008","journal-title":"J Vasc Interv Neurol"},{"key":"2024052222434602000_2.3.192.5","first-page":"521","article-title":"Urgent stenting of the M2 (superior) division of the middle cerebral artery after systemic thrombolysis in acute stroke","volume":"27","author":"Gupta","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222434602000_2.3.192.6","first-page":"1882","article-title":"Intracranial angioplasty and stenting: long-term results from a single center","volume":"27","author":"Wojak","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222434602000_2.3.192.7","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.18.1875"},{"key":"2024052222434602000_2.3.192.8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/MCA.0b013e328329dc20","article-title":"Safety and efficacy of 2.5\u00e2\u0080\u0085mm sirolimus-eluting stent implantation at lower deployment pressures in very small vessels (<2.5\u00e2\u0080\u0085mm)","volume":"20","author":"Umeda","year":"2009","journal-title":"Coron Artery Dis"},{"key":"2024052222434602000_2.3.192.9","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000257963.65728.e8"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnis.2009.001818","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T02:30:17Z","timestamp":1716431417000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/jnis.2009.001818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,4]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,8,26]]},"published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1136\/jnis.2009.001818"],"URL":"https:\/\/doi.org\/10.1136\/jnis.2009.001818","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,4]]}}}