{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:00:37Z","timestamp":1768968037411,"version":"3.49.0"},"reference-count":11,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2010,3,19]]},"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:p>Acute basilar artery occlusion (ABAO) is a devastating disease that can produce significant brainstem injury. Pretreatment diffusion weighted imaging (DWI) demonstrating extensive brainstem involvement has been shown to predict a poor outcome regardless of reperfusion. This case report describes a patient presenting with coma secondary to ABAO. MRI at presentation demonstrated significant DWI abnormality in the majority of the bilateral pons. The basilar artery was endovascularly recanalized 8\u2005h after stroke onset, and the patient had a marked clinical recovery with no deficit at 3\u2005months. Follow-up imaging revealed significant reversal of the pontine lesion. This finding of brainstem DWI reversibility cautions against the use of DWI to select ABAO patients for intra-arterial stroke therapy. The degree of apparent diffusion coefficient reduction on pretreatment MRI may not adequately identify which DWI abnormal brainstem tissue is potentially reversible.<\/jats:p>","DOI":"10.1136\/jnis.2009.002048","type":"journal-article","created":{"date-parts":[[2010,6,5]],"date-time":"2010-06-05T00:26:22Z","timestamp":1275697582000},"page":"195-197","source":"Crossref","is-referenced-by-count":25,"title":["Diffusion weighted imaging reversibility in the brainstem following successful recanalization of acute basilar artery occlusion"],"prefix":"10.1136","volume":"2","author":[{"given":"Albert J","family":"Yoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Hakimelahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia S","family":"Rost","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela W","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua A","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Gilberto","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D","family":"Rabinov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,6,4]]},"reference":[{"key":"2024052222452968000_2.3.195.1","first-page":"2042","article-title":"Outcome of acute vertebrobasilar occlusions treated with intra-arterial fibrinolysis in 180 patients","volume":"27","author":"Schulte-Altedorneburg","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222452968000_2.3.195.2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.517680"},{"key":"2024052222452968000_2.3.195.3","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1278"},{"key":"2024052222452968000_2.3.195.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000177515.14055.d0"},{"key":"2024052222452968000_2.3.195.5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181b6bb33"},{"key":"2024052222452968000_2.3.195.6","first-page":"951","article-title":"Characterization and evolution of diffusion MR imaging abnormalities in stroke patients undergoing intra-arterial thrombolysis","volume":"25","author":"Schaefer","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024052222452968000_2.3.195.7","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200004)47:4<462::AID-ANA9>3.0.CO;2-Y"},{"key":"2024052222452968000_2.3.195.8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000114873.28023.C2"},{"key":"2024052222452968000_2.3.195.9","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10380"},{"key":"2024052222452968000_2.3.195.10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1148\/radiol.2211001523","article-title":"Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain","volume":"221","author":"Grant","year":"2001","journal-title":"Radiology"},{"key":"2024052222452968000_2.3.195.11","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg166"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnis.2009.002048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T06:35:08Z","timestamp":1716446108000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/jnis.2009.002048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,4]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,8,26]]},"published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1136\/jnis.2009.002048"],"URL":"https:\/\/doi.org\/10.1136\/jnis.2009.002048","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,4]]}}}