{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:03:24Z","timestamp":1761393804486},"reference-count":32,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pract Neurol"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:p>M\u00e9ni\u00e8re\u2019s disease affects about 1% of the population. Typically it presents as episodic vertigo, fluctuating hearing loss, tinnitus and aural fullness. The history and physical examination are critical in making the diagnosis. Laboratory tests are useful in tailoring and following up patients. Treatment options are limited and usually targeted towards reducing endolymphatic hydrops to stabilise the hearing loss and reduce the vertiginous episodes.<\/jats:p>","DOI":"10.1136\/jnnp.2009.176602","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T17:25:22Z","timestamp":1242408322000},"page":"157-162","source":"Crossref","is-referenced-by-count":16,"title":["M\u00e9ni\u00e8re\u2019s disease"],"prefix":"10.1136","volume":"9","author":[{"given":"M A","family":"Hamid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"2024052910362416000_9.3.157.1","first-page":"72","article-title":"The natural course of M\u00e9ni\u00e8re\u2019s disease.","volume":"406","author":"Friberg","year":"1984","journal-title":"Acta Otolaryngol Suppl"},{"key":"2024052910362416000_9.3.157.2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3109\/00016489109128047","article-title":"Long-term progression of M\u00e9ni\u00e8re\u2019s disease.","volume":"485","author":"Stahle","year":"1991","journal-title":"Acta Otolaryngol Suppl"},{"key":"2024052910362416000_9.3.157.3","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/019459988809800308","article-title":"Autoimmune endolymphatic hydrops: five-year review.","volume":"98","author":"Hughes","year":"1988","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2024052910362416000_9.3.157.4","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/01.mao.0000226315.27811.c8","article-title":"Familial M\u00e9ni\u00e8re\u2019s disease in five generations.","volume":"27","author":"Frykholm","year":"2006","journal-title":"Otol Neurotol"},{"key":"2024052910362416000_9.3.157.5","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/ajmg.b.30347","article-title":"A M\u00e9ni\u00e8re\u2019s disease gene linked to chromosome 12p12.3.","volume":"141B","author":"Klar","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"2024052910362416000_9.3.157.6","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1097\/MAO.0b013e318068b2dd","article-title":"Positive experiences associated with M\u00e9ni\u00e8re\u2019s disorder.","volume":"28","author":"Stephens","year":"2007","journal-title":"Otol Neurotol"},{"key":"2024052910362416000_9.3.157.7","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3109\/00016489509121906","article-title":"Epidemiological and clinical characteristics of M\u00e9ni\u00e8re\u2019s disease in Japan.","volume":"519","author":"Watanabe","year":"1995","journal-title":"Acta Otolaryngol Suppl"},{"key":"2024052910362416000_9.3.157.8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1017\/S0022215100067372","article-title":"Emotion as a precipitating factor in M\u00e9ni\u00e8re\u2019s disease.","volume":"81","author":"Hinchcliffe","year":"1967","journal-title":"J Laryngol Otol"},{"key":"2024052910362416000_9.3.157.9","first-page":"597","article-title":"Pathologie auricularie: memoire sur des lesions de l\u2019oreille interne donnant lieu a des symptomes de congestion cerebrate apoplectiforme. [abstract].","volume":"16","author":"M\u00e9ni\u00e8re\u2019s","year":"1861","journal-title":"Gaz Med Paris"},{"key":"2024052910362416000_9.3.157.10","first-page":"2310","article-title":"Uber die pathologische Veranderung bei einem Meniere-Kranken [abstract].","volume":"44","author":"Yamakawa","year":"1938","journal-title":"L Otorhinolaryngol Spc Jpn"},{"key":"2024052910362416000_9.3.157.11","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100003947"},{"key":"2024052910362416000_9.3.157.12","first-page":"1","article-title":"Endolymphatic hydrops. An overview and classification.","volume":"106","author":"Schuknecht","year":"1983","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"2024052910362416000_9.3.157.13","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909801108"},{"key":"2024052910362416000_9.3.157.14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0711463105"},{"key":"2024052910362416000_9.3.157.15","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1002\/lary.1977.87.11.1870","article-title":"Old and new in M\u00e9ni\u00e8re disease.","volume":"87","author":"Torok","year":"1977","journal-title":"Laryngoscope"},{"key":"2024052910362416000_9.3.157.16","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3109\/00016487909126442","article-title":"M\u00e9ni\u00e8re\u2019s disease: etiology and natural history.","volume":"87","author":"Schmidt","year":"1979","journal-title":"Acta Otolaryngol"},{"key":"2024052910362416000_9.3.157.17","first-page":"453","article-title":"[Natural history of M\u00e9ni\u00e8re\u2019s disease concerning 92 cases from 1971 to 1980].","volume":"110","author":"Charachon","year":"1989","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"2024052910362416000_9.3.157.18","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/019459988910000102","article-title":"Natural history vs. surgery for M\u00e9ni\u00e8re\u2019s disease.","volume":"100","author":"Silverstein","year":"1989","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2024052910362416000_9.3.157.19","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1177\/019459989110400603","article-title":"Longitudinal follow up of patients with M\u00e9ni\u00e8re\u2019s disease.","volume":"104","author":"Green","year":"1991","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2024052910362416000_9.3.157.20","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32830ce796"},{"key":"2024052910362416000_9.3.157.21","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70102-8"},{"key":"2024052910362416000_9.3.157.22","doi-asserted-by":"crossref","unstructured":"Hamid M Sismanis A . Clinical Approach to Patients with Auditory and Vestibular Disorders. In: Hamid M Sismanis A , eds. Medical otology and neurotology. A clinical guide to auditory and vestibular disorders. New York: Thieme, 2006:43\u201363.","DOI":"10.1055\/b-002-96300"},{"key":"2024052910362416000_9.3.157.23","doi-asserted-by":"publisher","DOI":"10.1080\/00016480510040137"},{"key":"2024052910362416000_9.3.157.24","doi-asserted-by":"publisher","DOI":"10.1258\/0022215053419871"},{"key":"2024052910362416000_9.3.157.25","doi-asserted-by":"crossref","unstructured":"Hamid M . Recent advances in medical otology-neurotology. Mediterr J Otol 2005:145\u201353.","DOI":"10.1055\/b-002-96300"},{"key":"2024052910362416000_9.3.157.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2005.10.006"},{"key":"2024052910362416000_9.3.157.27","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1258\/0022215042244822","article-title":"M\u00e9ni\u00e8re\u2019s disease and allergy: allergens and cytokines.","volume":"118","author":"Keles","year":"2004","journal-title":"J Laryngol Otol"},{"key":"2024052910362416000_9.3.157.28","first-page":"208","article-title":"Betahistine in the treatment of vertiginous syndromes: a meta-analysis.","volume":"26","author":"Della","year":"2006","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"2024052910362416000_9.3.157.29","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31815aea05"},{"key":"2024052910362416000_9.3.157.30","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/014556130308200311","article-title":"Changing trends in the surgical treatment of M\u00e9ni\u00e8re\u2019s disease: results of a 10-year survey.","volume":"82","author":"Silverstein","year":"2003","journal-title":"Ear Nose Throat J"},{"key":"2024052910362416000_9.3.157.31","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200407000-00023"},{"key":"2024052910362416000_9.3.157.32","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00008"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.2009.176602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T17:36:41Z","timestamp":1717004201000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/jnnp.2009.176602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,15]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,5,15]]},"published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1136\/jnnp.2009.176602"],"URL":"https:\/\/doi.org\/10.1136\/jnnp.2009.176602","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,15]]}}}